Evidence map›Paper›PMID 31978518›Full record

ArticleMagnetic resonance imaging2020

Measuring the link between cardiac mechanical function and metabolism during hyperpolarized

Gregory P Barton, Erin B Macdonald, Kara N Goss, Marlowe W Eldridge, Sean B Fain

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Gregory P BartonMedical Physics, University of Wisconsin, Madison, WI, USA.
Erin B MacdonaldMedical Physics, University of Wisconsin, Madison, WI, USA.
Kara N GossMedicine University of Wisconsin, Madison, WI, USA; Pediatrics University of Wisconsin, Madison, WI, USA.
Marlowe W EldridgePediatrics University of Wisconsin, Madison, WI, USA; Biomedical Engineering, University of Wisconsin, Madison, WI, USA.
Sean B FainMedical Physics, University of Wisconsin, Madison, WI, USA; Biomedical Engineering, University of Wisconsin, Madison, WI, USA; Radiology, University of Wisconsin, Madison, WI, USA. Electronic address: sfain@wisc.edu.
University of Wisconsin–Madison · US

Funding

University of Wisconsin Institute for Clinical and Translational ResearchUL1TR002373 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI ELIZABETH S BURNSIDE, Allan R. Brasier · 2017 to 2026
$75.9M
Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
NRSA Training CoreTL1TR002375 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI Vivek Prabhakaran · 2017 to 2026
$8.4M
Wisconsin Allergy Research Training (WISCART) ProgramT32AI007635 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI James E. Gern, DANIEL J JACKSON · 2000 to 2026
$6.5M
Institutional Clinical and Translational Science Award (UW-Madison)(TL1)TL1RR025013 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2007 to 2011
$1.1M
NCATS NIH HHS TL1 TR002375NCATS NIH HHS UL1 TR000427NCATS NIH HHS UL1 TR002373NCRR NIH HHS TL1 RR025013NIAID NIH HHS T32 AI007635
6 · The paper itself

Abstract

purposeThe goal of this study was to develop a methodology to investigate the relationship between contractile function and hyperpolarized (HP) [1-

methodsEight female Sprague Dawley rats were imaged on a 4.7T scanner with a dual tuned

resultsWe demonstrated significant changes in cardiac contractile function between pre- and post-infusion of [1-

conclusionThe infusion of [1-

Indexed as

Magnetic Resonance Imaging, CineAnimalsArea Under CurveBicarbonatesCarbon IsotopesFemaleHeartHeart VentriclesLactic AcidMyocardiumPyruvic AcidRatsRats, Sprague-DawleyBicarbonatesCarbon-13Carbon IsotopesLactic AcidPyruvic AcidCarbon-13Contractile functionHyperpolarizedK-t spiralMetabolismMRSI

Identifiers

PMID31978518
PMCPMC7131884
OpenAlexW3002814365

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.