Evidence map›Paper›PMID 31978350›Full record

ArticleCell2020

An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma.

Henry R Maun, Janet K Jackman, David F Choy, Kelly M Loyet, Tracy L Staton, Guiquan Jia, Amy Dressen, Jason A Hackney, Meire Bremer, Benjamin T Walters and 40 more

Abstract readPublished Erratum
PubMed Publisher
In one paragraph

Article in Cell, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Emerging Therapies for Anaphylaxis.Immunology and allergy clinics of North America · 2026
    Review
  2. Proteases in intestinal health and disease.Nature reviews. Gastroenterology & hepatology · 2026
    Review
  3. Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

50 authors.

Henry R Maun
Janet K Jackman
David F Choy
Kelly M Loyet
Tracy L Staton
Guiquan Jia
Amy Dressen
Jason A Hackney
Meire Bremer
Benjamin T Walters
Rajesh Vij
Xiaocheng Chen
Neil N Trivedi
Ashley Morando
Michael T Lipari
Yvonne Franke
Xiumin Wu
Juan Zhang
John Liu
Ping Wu
Diana Chang
Luz D Orozco
Erin Christensen
Manda Wong
Racquel Corpuz
Julie Q Hang
Jeff Lutman
Siddharth Sukumaran
Yan Wu
Savita Ubhayakar
Xiaorong Liang
Lawrence B Schwartz
Magda Babina
Prescott G Woodruff
John V Fahy
Rahul Ahuja
George H Caughey
Aija Kusi
Mark S Dennis
Charles Eigenbrot
Daniel Kirchhofer
Cary D Austin
Lawren C Wu
James T Koerber
Wyne P Lee
Brian L Yaspan
Kathila R Alatsis
Joseph R Arron
Robert A Lazarus
Tangsheng Yi

Funding

Understanding Asthma EndotypesU19AI077439 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI David J Erle · 2008 to 2026
$41.1M
Role of miRNAs in Th2-Driven inflammation in AsthmaP01HL107202 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FAHY, JOHN V · 2012 to 2023
$23.3M
NHLBI NIH HHS P01 HL107202NIAID NIH HHS U19 AI077439
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.