Evidence map›Paper›PMID 31978276›Full record

ArticleJournal of clinical laboratory analysis2020

Association of the genetic variants (-794 CATT5-8 and -173 G > C) of macrophage migration inhibitory factor (MIF) with higher soluble levels of MIF and TNFα in women with breast cancer.

Guadalupe Avalos-Navarro, Alicia Del Toro-Arreola, Adrián Daneri-Navarro, Antonio Quintero-Ramos, Luis Alberto Bautista-Herrera, Ramon Antonio Franco Topete, Brian Uriel Anaya Macias, David Israel Javalera Castro, Andrés de Jesús Morán-Mendoza, Antonio Oceguera-Villanueva and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical laboratory analysis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Serum α1-AT Levels andDiseases (Basel, Switzerland) · 2024
    Article
  4. Article
  5. Review
  6. Haplotypes of [-794(CATT)Molecular genetics & genomic medicine · 2023
    Article
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Guadalupe Avalos-NavarroLaboratorio de Inmunología, Departamento de Fisiología, CUCS, Universidad de Guadalajara, Guadalajara, México.
Alicia Del Toro-ArreolaLaboratorio de Inmunología, Departamento de Fisiología, CUCS, Universidad de Guadalajara, Guadalajara, México.
Adrián Daneri-NavarroLaboratorio de Inmunología, Departamento de Fisiología, CUCS, Universidad de Guadalajara, Guadalajara, México.
Antonio Quintero-RamosLaboratorio de Inmunología, Departamento de Fisiología, CUCS, Universidad de Guadalajara, Guadalajara, México.
Luis Alberto Bautista-HerreraDepartamento de Biología Molecular y Genómica, Instituto de Investigación en Ciencias Biomédicas (IICB), Universidad de Guadalajara, Guadalajara, México.
Ramon Antonio Franco TopeteLaboratorio de Patología, Departamento de Patología y Microbiología, CUCS, Universidad de Guadalajara, Guadalajara, México.
Brian Uriel Anaya MaciasDepartamento de Biología Molecular y Genómica, Instituto de Investigación en Ciencias Biomédicas (IICB), Universidad de Guadalajara, Guadalajara, México.
David Israel Javalera CastroLaboratorio de Inmunología, Departamento de Fisiología, CUCS, Universidad de Guadalajara, Guadalajara, México.
Andrés de Jesús Morán-MendozaHospital de Especialidades, Centro Médico Nacional de Occidente, IMSS, Guadalajara, Mexico.
Antonio Oceguera-VillanuevaInstituto Jalisciense de Cancerología, Secretaría de Salud, Guadalajara, Mexico.
Antonio Topete-CamachoLaboratorio de Inmunología, Departamento de Fisiología, CUCS, Universidad de Guadalajara, Guadalajara, México.
José Francisco Muñoz-ValleDepartamento de Biología Molecular y Genómica, Instituto de Investigación en Ciencias Biomédicas (IICB), Universidad de Guadalajara, Guadalajara, México.ORCID https://orcid.org/0000-0002-2272-9260
Universidad de Guadalajara · MXHospital de Especialidades · MXSecretaria de Salud · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFunctional variants -173 G > C (rs755622) and -794CATT MATERIALS AND

methodsA total of 152 women with BC and 182 control subjects (CS) were enrolled in this study. The determination of genotypes -173 G > C and -794 CATT

resultsThe most frequent allele found in BC was the G (74.3%) and 6 (54%) in the variants -173G > C and -794 CATT

conclusionThe functional variants of MIF are not genetic susceptibility markers for BC. Nevertheless, the alleles -173*C and -794CATT

Indexed as

AdultBreast NeoplasmsCase-Control StudiesCross-Sectional StudiesFemaleGene FrequencyGenetic Predisposition to DiseaseHumansIntramolecular OxidoreductasesMacrophage Migration-Inhibitory FactorsMexicoMiddle AgedPolymorphism, GeneticPolymorphism, Restriction Fragment LengthSolubilityTumor Necrosis Factor-alphaIntramolecular OxidoreductasesMacrophage Migration-Inhibitory FactorsMIF protein, humanTNF protein, humanTumor Necrosis Factor-alphabreast cancermigration inhibitory factorpolymorphismsoluble levelsTNFa

Identifiers

PMID31978276
PMCPMC7246356
OpenAlexW3001172792

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.