Evidence map›Paper›PMID 31978173›Full record

ArticlePloS one2020

Machine learning detection of Atrial Fibrillation using wearable technology.

Mark Lown, Michael Brown, Chloë Brown, Arthur M Yue, Benoy N Shah, Simon J Corbett, George Lewith, Beth Stuart, Michael Moore, Paul Little

Open access · goldAbstract readValidation Study
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.

  1. Pooled it
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  11. Wearable activity trackers-advanced technology or advanced marketing?European journal of applied physiology · 2022
    Review
  12. Is machine learning the future for atrial fibrillation screening?Cardiovascular digital health journal · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Mark LownPrimary Care & Population Sciences, Faculty of Medicine, University of Southampton, Southampton, England.ORCID 0000-0001-8309-568X
Michael BrownLeonardo MW Ltd, Southampton, England.
Chloë BrownPrimary Care & Population Sciences, Faculty of Medicine, University of Southampton, Southampton, England.ORCID 0000-0002-9229-3351
Arthur M YueCardiology and Electrophysiology, Southampton General Hospital, Southampton, England.
Benoy N ShahCardiology and Electrophysiology, Southampton General Hospital, Southampton, England.
Simon J CorbettCardiology and Electrophysiology, Southampton General Hospital, Southampton, England.
George LewithCardiology and Electrophysiology, Southampton General Hospital, Southampton, England.
Beth StuartPrimary Care & Population Sciences, Faculty of Medicine, University of Southampton, Southampton, England.
Michael MoorePrimary Care & Population Sciences, Faculty of Medicine, University of Southampton, Southampton, England.
Paul LittlePrimary Care & Population Sciences, Faculty of Medicine, University of Southampton, Southampton, England.
University of Southampton · GBSouthampton General Hospital · GBLeonardo (United Kingdom) · GB

Funding

Department of Health 318
6 · The paper itself

Abstract

backgroundAtrial Fibrillation is the most common arrhythmia worldwide with a global age adjusted prevalence of 0.5% in 2010. Anticoagulation treatment using warfarin or direct oral anticoagulants is effective in reducing the risk of AF-related stroke by approximately two-thirds and can provide a 10% reduction in overall mortality. There has been increased interest in detecting AF due to its increased incidence and the possibility to prevent AF-related strokes. Inexpensive consumer devices which measure the ECG may have the potential to accurately detect AF but do not generally incorporate diagnostic algorithms. Machine learning algorithms have the potential to improve patient outcomes particularly where diagnoses are made from large volumes or complex patterns of data such as in AF.

methodsWe designed a novel AF detection algorithm using a de-correlated Lorenz plot of 60 consecutive RR intervals. In order to reduce the volume of data, the resulting images were compressed using a wavelet transformation (JPEG200 algorithm) and the compressed images were used as input data to a Support Vector Machine (SVM) classifier. We used the Massachusetts Institute of Technology (MIT)-Beth Israel Hospital (BIH) Atrial Fibrillation database and the MIT-BIH Arrhythmia database as training data and verified the algorithm performance using RR intervals collected using an inexpensive consumer heart rate monitor device (Polar-H7) in a case-control study.

resultsThe SVM algorithm yielded excellent discrimination in the training data with a sensitivity of 99.2% and a specificity of 99.5% for AF. In the validation data, the SVM algorithm correctly identified AF in 79/79 cases; sensitivity 100% (95% CI 95.4%-100%) and non-AF in 328/336 cases; specificity 97.6% (95% CI 95.4%-99.0%).

conclusionsAn inexpensive wearable heart rate monitor and machine learning algorithm can be used to detect AF with very high accuracy and has the capability to transmit ECG data which could be used to confirm AF. It could potentially be used for intermittent screening or continuously for prolonged periods to detect paroxysmal AF. Further work could lead to cost-effective and accurate estimation of AF burden and improved risk stratification in AF.

Indexed as

Diagnosis, Computer-AssistedSupport Vector MachineWearable Electronic DevicesAgedAtrial FibrillationCase-Control StudiesElectrocardiographyHumans

Identifiers

PMID31978173
PMCPMC6980577
OpenAlexW3001838300

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.