Evidence map›Paper›PMID 31977922›Full record

ArticleJournal of occupational and environmental medicine2020

Respiratory Diseases in Post-9/11 Military Personnel Following Southwest Asia Deployment.

Silpa D Krefft, Jenna Wolff, Lauren Zell-Baran, Matthew Strand, Eva Brigitte Gottschall, Richard Meehan, Cecile Stephanie Rose

Registry-linked trialAbstract read
In one paragraph

Article in Journal of occupational and environmental medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03035097 (Deployment-Related Lung Disease Research Database and Biorepository), which is not on this map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03035097 recruitingnot on this map

Deployment-Related Lung Disease Research Database and Biorepository

Typeobservational_patient_registrySponsorNational Jewish HealthRan2013 to 2030Enrolled500ConditionsBronchiolitisArmsBiorepository
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Deployment-Related Respiratory Disease: Where Are We?Seminars in respiratory and critical care medicine · 2023
    Review
  12. Article
  13. Article
  14. Article
  15. A Clinician's Guide to Occupational Exposures in the Military.Current allergy and asthma reports · 2022
    Review
  16. Article
  17. Article
  18. Burn Pit Exposure Is Associated With Increased Sinonasal Disease.Journal of occupational and environmental medicine · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Silpa D KrefftNational Jewish Health, Denver (Dr Krefft, Ms Wolff, Ms Zell-Baran, Dr Strand, Dr Gottschall, Dr Meehan, Dr Rose); Veterans Administration Eastern Colorado Health Care System (Dr Krefft); University of Colorado Anschutz Medical Campus (Dr Krefft, Dr Rose); Colorado School of Public Health (Dr Krefft, Ms Zell-Baran, Dr Strand, Dr Rose); University of Colorado (Dr Gottschall, Dr Meehan), Aurora, Colorado.
Jenna Wolff
Lauren Zell-Baran
Matthew Strand
Eva Brigitte Gottschall
Richard Meehan
Cecile Stephanie Rose
Drip Research Technology Services (United States) · US

Funding

NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
NCATS NIH HHS UL1 TR002535
6 · The paper itself

Abstract

objectivePersistent respiratory symptoms following post-9/11 military deployment to Iraq and Afghanistan are well-recognized, but the spectrum of respiratory diseases remains poorly characterized. This study describes deployment-related respiratory diseases and the diagnostic utility of resting and exercise pulmonary function testing.

methodsBetween 2009 and 2017, 127 consecutive military workers ("deployers") with new-onset respiratory symptoms underwent clinical evaluation. Deployment-related respiratory diseases were classified as proximal and/or distal. Using descriptive statistics and logistic regression, we analyzed lung function parameters associated with deployment-related distal lung disease (DDLD).

resultsCommon deployment-related respiratory diseases included asthma (31.5%), intermittent laryngeal obstruction (14.2%), rhinosinusitis (15%), and DDLD (68.5%). Decreased diffusion capacity (odds ratio [OR] = 4.6, 95% confidence interval [CI]: 1.4 to 15.1, P = 0.01) was significantly associated with DDLD.

conclusionsA comprehensive diagnostic approach may identify a spectrum of proximal and distal respiratory diseases that can occur in symptomatic post-9/11 deployers, requiring a personalized approach to care.

Indexed as

AdultAfghan Campaign 2001-AgedFemaleHumansIraq War, 2003-2011LungMaleMiddle AgedMilitary PersonnelOccupational DiseasesOdds RatioRespiration DisordersUnited StatesWar ExposureYoung Adult

Identifiers

PMID31977922
PMCPMC11998598
OpenAlexW3002898276

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.