Evidence map›Paper›PMID 31977899›Full record

Observational studyMedicine2020

A retrospective comparative study of infection control rate and clinical outcome between open debridement using antibiotic-impregnated cement beads and a two-stage revision in acute periprosthetic knee joint infection.

Moon Jong Chang, Seung Ah Lee, Seung-Baik Kang, Keum Min Hwang, Hyung Jun Park, Kyoung Hwan Lee, Jai Gon Seo, Chong Bum Chang

Open access · goldAbstract readComparative StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Moon Jong ChangDepartment of Orthopedic Surgery, Seoul National University College of Medicine, SMG-SNU Boramae Medical Center.
Seung Ah LeeDepartment of Physical Medicine and Rehabilitation, College of Medicine, Kyung Hee University.
Seung-Baik KangDepartment of Orthopedic Surgery, Seoul National University College of Medicine, SMG-SNU Boramae Medical Center.
Keum Min HwangDepartment of Orthopedic Surgery, Seoul National University College of Medicine, SMG-SNU Boramae Medical Center.
Hyung Jun ParkDepartment of Orthopedic Surgery, Seoul National University College of Medicine, SMG-SNU Boramae Medical Center.
Kyoung Hwan LeeDepartment of Orthopedic Surgery, Seoul National University College of Medicine, SMG-SNU Boramae Medical Center.
Jai Gon SeoDepartment of Orthopedic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Chong Bum ChangDepartment of Orthopedic Surgery, Seoul National University College of Medicine, SMG-SNU Boramae Medical Center.
National University College · PRSeoul National University · KRKyung Hee University · KRNew Generation University College · ETSamsung Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to determine whether the infection control rate of a modified debridement, antibiotics, and implant retention (DAIR) protocol (DAIR with antibiotic-impregnated cement beads) is comparable to that of 2-stage revision for acute periprosthetic joint infection (PJI) after total knee arthroplasty (TKA). We also aimed to determine whether this modified DAIR technique produced better clinical results than those obtained using 2-stage revision in terms of functional outcome, range of motion (ROM), and patient satisfaction at 2 years after surgery.This retrospective comparative study included patients who underwent modified DAIR (7 patients, 9 knees) or 2-stage revision (8 patients, 9 knees) for acute PJI of the knee joint. Infection control rate, functional outcome measured using Western Ontario and McMaster Universities Arthritis Index (WOMAC) score, ROM and patient satisfaction were compared between the two groups.There was no difference in infection control rates between the modified DAIR and 2-stage revision groups (78% vs 78%, respectively). In contrast, surgical outcome in the modified DAIR group was tended to be better than 2-stage revision group, but it did not reach statistical significance. Median maximal range of flexion was 103° in the modified DAIR group and it was 90° in the 2-stage group (P = .191). In addition, the median WOMAC function score was 24 in the modified DAIR group and it was 30 in the 2-stage group (P = .076). Median patient satisfaction measured using visual analogue scale was 8 in the modified DAIR group and 5 in the 2-stage group (P = .069).The infection control rates of the modified DAIR protocol and 2-stage revision protocol were similar for the treatment of acute PJI of the knee joint. However, the modified DAIR protocol could not provide substantially increased functional outcomes and patient satisfaction compared to 2-stage revision. Therefore, the modified DAIR technique should be considered to be of limited use in patients with high surgical morbidity.

Indexed as

Prosthesis-Related InfectionsAgedAged, 80 and overAnti-Bacterial AgentsArthroplasty, Replacement, KneeBone CementsDebridementFemaleHumansKnee JointMaleMiddle AgedReoperationRetrospective StudiesTreatment OutcomeVancomycinAnti-Bacterial AgentsBone CementsVancomycin

Identifiers

PMID31977899
PMCPMC7004723
OpenAlexW3002403873

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.