Trial reportMedicine2020
An integrative cognitive rehabilitation using neurologic music therapy in multiple sclerosis: A pilot study.
Trial report in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 6 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Potential benefits of music-based therapies on rehabilitation outcomes in people with multiple sclerosis: a systematic review.BMJ open · 2026Pooled it
- The Effect of Music Therapy on Psychological Outcomes for Neurological Conditions: A Systematic Review.Medicina (Kaunas, Lithuania) · 2025Pooled it
- The efficacy of music therapy in alleviating anxiety among college students: a systematic review and meta-analysis.Frontiers in psychology · 2025Pooled it
- A systematic review and meta-analysis of the effects of non-pharmacological interventions on quality of life in adults with multiple sclerosis.European journal of medical research · 2023Pooled it
- Memory rehabilitation for people with multiple sclerosis.The Cochrane database of systematic reviews · 2021Pooled it
- Music-based therapy in rehabilitation of people with multiple sclerosis: a systematic review of clinical trials.Arquivos de neuro-psiquiatria · 2021Pooled it
- Review
- Effectiveness of Telecoaching and Music Therapy in Neurological Disorders: A Narrative Review and Proposal for a New Interventional Approach.Healthcare (Basel, Switzerland) · 2025Review
- Delivery of Neuropsychological Interventions for Adult and Older Adult Clinical Populations: An Australian Expert Working Group Clinical Guidance Paper.Neuropsychology review · 2024Review
- Effects of movement training based on rhythmic auditory stimulation in cognitive impairment: a meta-analysis of randomized controlled clinical trial.Frontiers in neuroscience · 2024Review
- Neurologic Music Therapy in Geriatric Rehabilitation: A Systematic Review.Healthcare (Basel, Switzerland) · 2022Review
- Non-Pharmacological Treatments of Cognitive Impairment in Multiple Sclerosis: A Review.NeuroSci · 2022Review
- Patient and Provider Insights into the Impact of Multiple Sclerosis on Mental Health: A Narrative Review.Neurology and therapy · 2021Review
- The use of music for children and adolescents living with rare diseases in the healthcare setting: a scoping review study protocol.HRB open research · 2021Article
- Music therapy with a monochord in multiple sclerosis ("MUTIMS"):Multiple sclerosis journal - experimental, translational and clinicalArticle
- Effectiveness of cognitive rehabilitation in comparison with routine rehabilitation methods in patients with multiple sclerosis: A systematic review and meta-analysis.Multiple sclerosis journal - experimental, translational and clinicalReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMultiple sclerosis (MS) is a demyelinating disease, affecting both the sensorimotor and cognitive systems. The typical pattern of cognitive impairment includes reduced speed of information processing, decreased phonological and semantic speech fluency, deficits in verbal and visual episodic memory, as well as attention and executive dysfunctions. We aimed to investigate the influence of the neurologic music therapy (NMT) on mood, motivation, emotion status, and cognitive functions in patients with MS.
methodsThirty patients with MS were randomly divided in 2 groups: the control group (CG) undergoing conventional cognitive rehabilitation (CCR), 6 times a week for 8 weeks, and the experimental group (EG) undergoing CCR 3 times a week for 8 weeks plus NMT techniques, performed 3 times a week for 8 weeks. All the participants were submitted to the same amount of treatment. Each patient was evaluated before (baseline: T0) and immediately after the end of each training (T1). MAIN OUTCOMES MEASURES: We used as main outcome measure: the brief repeatable battery of neuropsychological test to assess various cognitive abilities; and the multiple sclerosis quality of life-54 (MSQoL-54).
resultsBoth the groups benefit from 8 weeks of CR. In particular, the EG got better results in cognitive function, with regard to selective reminding test long term storage (P < .000), long term retrieval (P = .007), and delayed recall of the 10/36 spatial recall test (P = .001), as compared with the CG. Moreover, the improvement in emotional status, motivation, mood and quality of life (with regard to the mental component; P < .000) was more evident in the EG.
conclusionsNMT could be considered a complementary approach to enhance CCR in patients affected by MS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.