Evidence map›Paper›PMID 31977498›Full record

ArticleDermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]2020

Postoperative Infections in Dermatologic Surgery: The Role of Wound Cultures.

Kimberly M Ken, Mariah M Johnson, Justin J Leitenberger, Donald E Neal, Jeremy R Etzkorn, Panayiota Govas, Bryan T Carroll, Ahmed H Badawi, Tejaswi Mudigonda, M Laurin Council and 5 more

Abstract readMulticenter Study
In one paragraph

Article in Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Kimberly M KenDepartment of Dermatology, Harry S. Truman Memorial Veterans' Hospital, University of Missouri, Columbia, Missouri.
Mariah M JohnsonDepartment of Dermatology, Oregon Health and Science University, Portland, Oregon.
Justin J LeitenbergerDepartment of Dermatology, Oregon Health and Science University, Portland, Oregon.
Donald E NealSidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania.
Jeremy R EtzkornDepartment of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania.
Panayiota GovasDepartment of Dermatology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Bryan T CarrollDepartment of Dermatology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Ahmed H BadawiDivision of Dermatology, Washington University in St. Louis, Saint Louis, Missouri.
Tejaswi MudigondaDivision of Dermatology, Washington University in St. Louis, Saint Louis, Missouri.
M Laurin CouncilDivision of Dermatology, Washington University in St. Louis, Saint Louis, Missouri.
Christina AvilaDivision of Dermatology, The Ohio State University Medical Center, Columba, Ohio.
David R CarrDivision of Dermatology, The Ohio State University Medical Center, Columba, Ohio.
Jodie SasakiDepartment of Dermatology, Emory University School of Medicine, Atlanta, Georgia.
Travis W BlalockDepartment of Dermatology, Emory University School of Medicine, Atlanta, Georgia.
Nicholas J GoldaDepartment of Dermatology, University of Missouri, Columbia, Missouri.

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR001857 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2016 to 2025
$129.3M
NCATS NIH HHS UL1 TR001857
6 · The paper itself

Abstract

backgroundDermatologic surgery is associated with low postoperative infection rates, averaging from approximately 1% to 4.25%. Often, postoperative infections are treated empirically based on clinical diagnosis of infection, given it can take 48 to 72 hours for a wound culture to identify a pathogen.

objectiveWe aimed to evaluate the efficacy of empiric antibiotics in dermatologic surgery postoperative infections and if wound cultures change postoperative antibiotic therapy.

methodsA 7-center, retrospective analysis of postoperative infections, with culture data, in dermatologic surgery patients was performed.

resultsOf 91 cases of clinically diagnosed postoperative infection, 82.4% (n = 75) were successfully treated with empiric oral antibiotics (95% confidence interval [0.73-0.89], p < .0001). In 16 (17.6%) cases, initial empiric antibiotics were unsuccessful, and wound culture results altered antibiotic therapy in 9 cases (9.9%) with 6 (6.6%) of these cases requiring additional coverage for methicillin-resistant Staphylococcus aureus (MRSA).

conclusionEmpiric antibiotic treatment is usually appropriate for patients with postoperative surgical-site infections with wound cultures altering antibiotic management in a minority of cases. When empiric antibiotics fail, lack of MRSA coverage is usually the cause; therefore, providers should be aware of local MRSA prevalence and susceptibilities.

Indexed as

AdultAnti-Bacterial AgentsAntibiotic ProphylaxisBacteriological TechniquesDermatologic Surgical ProceduresDrug Resistance, BacterialFemaleHumansMaleMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsPrevalenceRetrospective StudiesSkin NeoplasmsSurgical Wound InfectionAnti-Bacterial Agents

Identifiers

PMID31977498
PMCPMC8439158

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.