Evidence map›Paper›PMID 31977208›Full record

ArticleJournal of medicinal chemistry2020

Identification of Psychoplastogenic

Lee E Dunlap, Arya Azinfar, Calvin Ly, Lindsay P Cameron, Jayashri Viswanathan, Robert J Tombari, Douglas Myers-Turnbull, Jack C Taylor, Ana Cristina Grodzki, Pamela J Lein and 2 more

Open access · greenAbstract read
In one paragraph

Article in Journal of medicinal chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 1 synthesis or guideline pooled it, 86 citations in OpenAlex.

  1. Pooled it
  2. Neural complexity is increased after low doses of LSD, but not moderate to high doses of oral THC or methamphetamine.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Trial
  3. Deconstruction of lysergic acid diethylamide.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. IndolethylamineACS chemical neuroscience · 2025
    Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Molecular design of a therapeutic LSD analogue with reduced hallucinogenic potential.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Lee E DunlapDepartment of Chemistry , University of California, Davis , One Shields Avenue , Davis , California 95616 , United States.
Arya AzinfarDepartment of Chemistry , University of California, Davis , One Shields Avenue , Davis , California 95616 , United States.
Calvin LyDepartment of Chemistry , University of California, Davis , One Shields Avenue , Davis , California 95616 , United States.
Lindsay P CameronNeuroscience Graduate Program , University of California, Davis , Davis , California 95618 , United States.
Jayashri ViswanathanDepartment of Chemistry , University of California, Davis , One Shields Avenue , Davis , California 95616 , United States.
Robert J TombariDepartment of Chemistry , University of California, Davis , One Shields Avenue , Davis , California 95616 , United States.ORCID 0000-0002-6561-8181
Douglas Myers-Turnbull
Jack C Taylor
Ana Cristina GrodzkiDepartment of Molecular Biosciences, School of Veterinary Medicine , University of California, Davis , 1089 Veterinary Medicine Drive , Davis , California 95616 , United States.
Pamela J LeinDepartment of Molecular Biosciences, School of Veterinary Medicine , University of California, Davis , 1089 Veterinary Medicine Drive , Davis , California 95616 , United States.ORCID 0000-0001-7665-7584
David KokelDepartment of Physiology , University of California, San Francisco , San Francisco , California 94158 , United States.
David E OlsonDepartment of Chemistry , University of California, Davis , One Shields Avenue , Davis , California 95616 , United States.ORCID 0000-0002-4517-0543
University of California, Davis · USUniversity of California, San Francisco · USQB3 · US

Funding

UC Davis Environmental Health Sciences Core CenterP30ES023513 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Nicholas J. KENYON · 2015 to 2026
$26.0M
Research Project: Pathologic Significance of Maternal AutoantibodiesP50HD103526 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI JUDY A. VAN DE WATER · 2020 to 2026
$9.7M
Rodent Behavior CoreU54HD079125 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI OZONOFF, SALLY · 2013 to 2019
$8.5M
Learning, Memory, and Plasticity (LaMP) Training ProgramT32MH112507 · NIMH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Karen Zito · 2017 to 2026
$2.4M
Design, Synthesis, and Evaluation of Neural Plasticity-Promoting Analogs of Iboga and Ergoline AlkaloidsR01GM128997 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI OLSON, DAVID E · 2018 to 2022
$1.8M
Behavior-based chemical screening for GABAergic and startle modifying drugsR01AA022583 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KOKEL, DAVID · 2013 to 2017
$1.6M
UC Davis Training Program in Chemical BiologyT32GM113770 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BEAL, PETER A. · 2015 to 2019
$742k
NIAAA NIH HHS R01 AA022583NICHD NIH HHS P50 HD103526NICHD NIH HHS U54 HD079125NIEHS NIH HHS P30 ES023513NIGMS NIH HHS R01 GM128997NIGMS NIH HHS T32 GM113770NIMH NIH HHS T32 MH112507
6 · The paper itself

Abstract

Ketamine,

Indexed as

AnimalsHallucinogensMiceMolecular StructureNeuronal PlasticityNeuronsN,N-DimethyltryptamineStructure-Activity RelationshipZebrafishHallucinogensN,N-Dimethyltryptamine

Identifiers

PMID31977208
PMCPMC7075704
OpenAlexW3002940062

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.