Evidence map›Paper›PMID 31977015›Full record

ReviewCardiovascular research2020

The pathogenic role of coronary microvascular dysfunction in the setting of other cardiac or systemic conditions.

Regina E Konst, Tomasz J Guzik, Juan-Carlos Kaski, Angela H E M Maas, Suzette E Elias-Smale

Open access · bronzeAbstract readReview
In one paragraph

Review in Cardiovascular research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 82 citations in OpenAlex.

  1. Review
  2. Covert macrovascular disease and early outcome after ischemic cerebrovascular events.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Regina E KonstDepartment of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands.
Tomasz J GuzikInstitute of Cardiovascular and Medical Sciences, British Heart Foundation Glasgow Cardiovascular Research Centre, Glasgow, UK.
Juan-Carlos KaskiThe Queen Elizabeth Hospital Discipline of Medicine, University of Adelaide, Central Adelaide Local Health Network, Coronary Vasomotion Disorders International Study Group (COVADIS), Adelaide, Australia.
Angela H E M MaasDepartment of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands.
Suzette E Elias-SmaleDepartment of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands.
Radboud University Nijmegen · NLBritish Heart Foundation · GBSt George's, University of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronary microvascular dysfunction (CMD) plays a pathogenic role in cardiac and systemic conditions other than microvascular angina. In this review, we provide an overview of the pathogenic role of CMD in the setting of diabetes mellitus, obesity, hypertensive pregnancy disorders, chronic inflammatory and autoimmune rheumatic disorders, chronic kidney disease, hypertrophic cardiomyopathy, and aortic valve stenosis. In these various conditions, CMD results from different structural, functional, and/or dynamic alterations in the coronary microcirculation associated with the primary disease process. CMD is often detectable very early in the course of the primary disease, before clinical symptoms or signs of myocardial ischaemia are present, and it portrays an increased risk for cardiovascular events.

Indexed as

Coronary CirculationMicrocirculationAnimalsCardiovascular DiseasesComorbidityCoronary VesselsDisease ProgressionFemaleHumansMaleMicrovesselsPregnancyPrognosisRisk FactorsComorbiditiesCoronary microvascular dysfunctionEndothelial dysfunctionInflammationMicrovascular angina

Identifiers

PMID31977015
PMCPMC7526753
OpenAlexW3002577956

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.