Evidence map›Paper›PMID 31976871›Full record

ReviewJournal of the American College of Cardiology2020

Marijuana Use in Patients With Cardiovascular Disease: JACC Review Topic of the Week.

Ersilia M DeFilippis, Navkaranbir S Bajaj, Amitoj Singh, Rhynn Malloy, Michael M Givertz, Ron Blankstein, Deepak L Bhatt, Muthiah Vaduganathan

Open access · greenAbstract readReview
In one paragraph

Review in Journal of the American College of Cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 1 pooled it
14.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 1 synthesis or guideline pooled it, 140 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Parasympathetic decreases immediately following self-reported cannabis smoking among adults living with cannabis use disorder.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2025
    Article
  10. Review
  11. Review
  12. Understanding the Role of Endocannabinoids in Posttraumatic Stress Disorder.International journal of molecular sciences · 2025
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Cardiovascular (side) effects of cannabis.Wiener klinische Wochenschrift · 2024
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Ersilia M DeFilippisColumbia University Irving Medical Center, New York, New York. Electronic address: https://twitter.com/ersied727.
Navkaranbir S BajajUniversity of Alabama at Birmingham, Birmingham, Alabama. Electronic address: https://twitter.com/bajaj_nav.
Amitoj SinghSarver Heart Center, University of Arizona, Tucson, Arizona.
Rhynn MalloyBrigham and Women's Hospital Heart & Vascular Center and Harvard Medical School, Boston, Massachusetts.
Michael M GivertzBrigham and Women's Hospital Heart & Vascular Center and Harvard Medical School, Boston, Massachusetts.
Ron BlanksteinBrigham and Women's Hospital Heart & Vascular Center and Harvard Medical School, Boston, Massachusetts. Electronic address: https://twitter.com/RonBlankstein.
Deepak L BhattBrigham and Women's Hospital Heart & Vascular Center and Harvard Medical School, Boston, Massachusetts. Electronic address: https://twitter.com/DLBHATTMD.
Muthiah VaduganathanBrigham and Women's Hospital Heart & Vascular Center and Harvard Medical School, Boston, Massachusetts. Electronic address: mvaduganathan@bwh.harvard.edu.
Twitter (United States) · USBrigham and Women's Hospital · USUniversity of Arizona · US

Funding

The Harvard Clinical and Translational Science CenterUL1TR002541 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2018 to 2022
$93.0M
NCATS NIH HHS UL1 TR002541
6 · The paper itself

Abstract

Marijuana use is increasing as more states are legalizing cannabis for both medicinal and recreational purposes. National survey data estimate that >2 million Americans with established cardiovascular diseases currently use or have used marijuana in its variety of forms, including inhalation and vaping. Cannabinoid receptors are distributed in multiple tissue beds and cells, including platelets, adipose tissue, and myocytes. Observational data suggest associations between marijuana and a broad range of adverse cardiovascular risks. Marijuana is becoming increasingly potent, and smoking marijuana carries many of the same cardiovascular health hazards as smoking tobacco. Synthetic cannabinoids have been linked to more sustained and deleterious pharmacodynamic effects. Marijuana is classified as a Schedule I substance, thus limiting its rigorous study for cardiovascular health effects. This review summarizes cardiovascular considerations related to marijuana use, pharmacological interactions, and future steps to provide clearer guidance regarding its cardiovascular safety. Screening for marijuana use is encouraged, especially in young patients presenting with cardiovascular disease.

Indexed as

Cardiovascular DiseasesHumansMarijuana UseNutrition SurveysUnited Statesarrhythmiacannabiscoronary artery diseasemarijuanavascular disease

Identifiers

PMID31976871
PMCPMC7977484
OpenAlexW2999076759

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.