Evidence map›Paper›PMID 31976603›Full record

SynthesisJournal of cardiovascular electrophysiology2020

The use of intracardiac echocardiography catheters in endocardial ablation of cardiac arrhythmia: Meta-analysis of efficiency, effectiveness, and safety outcomes.

Masahiko Goya, Diana Frame, Larry Gache, Yoko Ichishima, Daiane Oliveira Tayar, Laura Goldstein, Stephanie Hsiao Yu Lee

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of cardiovascular electrophysiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pulsed field ablation for the interventional treatment of atrial fibrillation: a scientific statement of the European Heart Rhythm Association of the European Society of Cardiology, the Heart Rhythm Society, the Asia Pacific Heart Rhythm Society, the Latin American Heart Rhythm Society, and the Canadian Heart Rhythm Society.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Guideline
  2. Intracardiac Echocardiography during Invasive Electrophysiological Procedures: a Scientific Statement of the European Heart Rhythm Association of the ESC, and the European Association of Percutaneous Cardiovascular Interventions of the ESC.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Guideline
  3. Pooled it
  4. Review
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  7. [Management of pericardial tamponade in the electrophysiology laboratory].Herzschrittmachertherapie & Elektrophysiologie · 2026
    Review
  8. Article
  9. Intracardiac versus transesophageal echocardiography in atrial fibrillation ablation: a systematic review and meta-analysis.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Review
  10. Intracardiac echocardiography for left ventricular diastolic function assessment during atrial fibrillation ablation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Masahiko GoyaDepartment of Cardiovascular Medicine, Tokyo Medical and Dental University, Tokyo, Japan.ORCID 0000-0002-7210-0671
Diana FrameReal World Evidence, CTI Clinical Trial & Consulting, Covington, Kentucky.
Larry GacheReal World Evidence, CTI Clinical Trial & Consulting, Covington, Kentucky.
Yoko IchishimaMedical Affairs, Johnson & Johnson K.K., Tokyo, Japan.
Daiane Oliveira TayarHealth Economics & Market Access, Johnson & Johnson Medical, São Paulo, Brazil.ORCID 0000-0002-3374-9291
Laura GoldsteinHealth Economics & Market Access, Johnson & Johnson Medical Devices, Irvine, California.ORCID 0000-0002-7847-0905
Stephanie Hsiao Yu LeeHealth Economics & Market Access, Johnson & Johnson Medical Asia Pacific, Singapore, Singapore.ORCID 0000-0003-0297-635X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe optimal use of intracardiac echocardiography (ICE) may reduce fluoroscopy time and procedural complications during endocardial ablation of cardiac arrhythmias. Due to limited evidence in this area, we conducted the first systematic literature review and meta-analysis to evaluate outcomes associated with the use of ICE. METHODS AND

resultsStudies reporting the use of ICE during ablation procedures vs without ICE were searched using PubMed/MEDLINE. A meta-analysis was performed on the 19 studies (2186 patients) meeting inclusion criteria, collectively representing a broad range of arrhythmia mechanisms. Use of ICE was associated with significant reductions in fluoroscopy time (Hedges' g -1.06; 95% confidence interval [CI] -1.81 to -0.32; P < .01), fluoroscopy dose (Hedges' g -1.27; 95% CI -1.91 to -0.62; P < .01), and procedure time (Hedges' g -0.35; 95% CI -0.64 to -0.05; P = .02) vs ablation without ICE. A 6.95 minute reduction in fluoroscopy time and a 15.2 minute reduction in procedure time was observed between the ICE vs non-ICE groups. These efficiency gains were not associated with any decreased effectiveness or safety. Sensitivity analyses limiting studies to an atrial fibrillation (AF) only population yielded similar results to the main analysis.

conclusionThe use of ICE in the ablation of cardiac arrhythmias is associated with significantly lower fluoroscopy time, fluoroscopy dose, and shorter procedure time vs ablation without ICE. These efficiency improvements did not compromise the clinical effectiveness or safety of the procedure.

Indexed as

Cardiac CathetersArrhythmias, CardiacCardiac CatheterizationCatheter AblationEchocardiographyFemaleFluoroscopyHumansMaleMiddle AgedOperative TimePredictive Value of TestsRadiation ExposureTreatment Outcomearrhythmiacatheter ablationICEintracardiac echocardiographyintracardiac ultrasound

Identifiers

PMID31976603
PMCPMC7078927

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.