Evidence map›Paper›PMID 31976355›Full record

ArticleOpen forum infectious diseases2020

Comparison of Multiplex Gastrointestinal Pathogen Panel and Conventional Stool Testing for Evaluation of Patients With HIV Infection.

Juliana Sobczyk, Sonia Jain, Xiaoying Sun, Maile Karris, Darcy Wooten, Janet Stagnaro, Sharon Reed

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Juliana SobczykDepartment of Pathology, University of California, San Diego, La Jolla, California, USA.
Sonia JainDepartment of Family Medicine and Public Health, University of California, San Diego, La Jolla, California, USA.
Xiaoying SunDepartment of Family Medicine and Public Health, University of California, San Diego, La Jolla, California, USA.
Maile KarrisDepartment of Internal Medicine, University of California, San Diego, La Jolla, California, USA.
Darcy WootenDepartment of Internal Medicine, University of California, San Diego, La Jolla, California, USA.
Janet StagnaroDepartment of Pathology, University of California, San Diego, La Jolla, California, USA.
Sharon ReedDepartment of Pathology, University of California, San Diego, La Jolla, California, USA.
University of California, San Diego · US

Funding

UC San Diego Clinical and Translational Research InstituteUL1TR001442 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S, HOGARTH, MICHAEL · 2015 to 2024
$88.3M
VirologyP30AI036214 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Maile Ann Young Karris · 1994 to 2026
$78.4M
NCATS NIH HHS UL1 TR001442NIAID NIH HHS P30 AI036214
6 · The paper itself

Abstract

backgroundGastrointestinal pathogen panels (GPPs) are increasingly used to identify stool pathogens, but their impact in people with HIV (PWH) is unknown. We performed a retrospective cohort study comparing GPP and conventional stool evaluation in PWH.

methodsWe included all PWH who underwent GPP (Biofire Diagnostics; implemented September 15, 2015) or conventional testing, including stool culture,

resultsOverall, 124 patient samples tested positive by GPP, compared with 45 patient specimens by conventional testing. The GPP group demonstrated a higher co-infection rate (48.4% vs 13.3%;

conclusionsIn PWH, GPP implementation improved antibiotic stewardship through shorter turnaround times and detection of enteric viral pathogens.

Indexed as

antibiotic stewardshipdiarrheagastrointestinal pathogen panelHIV

Identifiers

PMID31976355
PMCPMC6970129
OpenAlexW3000455843

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.