Evidence map›Paper›PMID 31976354›Full record

ArticleOpen forum infectious diseases2020

Pet Ownership Protects Against Recurrence of

Laurel E Redding, Brendan J Kelly, Darko Stefanovski, John K Lautenbach, Pam Tolomeo, Leigh Cressman, Eli Gruber, Paige Meily, Ebbing Lautenbach

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Risk Factors Associated with RecurrentHealthcare (Basel, Switzerland) · 2020
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Laurel E ReddingDepartment of Clinical Sciences, School of Veterinary Medicine, University of Pennsylvania, Pennsylvania, USA.ORCID 0000-0002-3414-1202
Brendan J KellyDivisions of Infectious Diseases and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Darko StefanovskiDepartment of Clinical Sciences, School of Veterinary Medicine, University of Pennsylvania, Pennsylvania, USA.
John K LautenbachWilliams College, Williamstown, Massachusetts, USA.
Pam TolomeoDivisions of Infectious Diseases and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Leigh CressmanCenter for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Eli GruberUniversity of Pennsylvania School of Arts and Sciences, Philadelphia, Pennsylvania, USA.
Paige MeilyUniversity of Pennsylvania School of Arts and Sciences, Philadelphia, Pennsylvania, USA.
Ebbing LautenbachDivisions of Infectious Diseases and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
University of Pennsylvania · USWilliams College · US

Funding

Longitudinal analysis of respiratory tract microbiome change and sequence-based infection diagnosis during mechanical ventilationK23AI121485 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI KELLY, BRENDAN JOSEPH · 2016 to 2020
$965k
NIAID NIH HHS K23 AI121485NIAID NIH HHS L30 AI120149
6 · The paper itself

Abstract

background

methodsWe conducted a case-control study among patients with recurrent CDI (cases; n = 86) and patients with nonrecurrent CDI (controls; n = 146). Multivariable logistic regression modeling was used to determine the association between recurrence of CDI and pet ownership while accounting for patient-level risk factors.

resultsPet ownership was not significantly associated with recurrence of CDI (odds ratio [OR], 1.02; 95% confidence interval [CI], 0.38-2.72;

conclusionsClose interactions with pets appear protective against the recurrence of community-acquired CDI. A potential mechanism may involve beneficial contributions to the microbiota of pet owners afflicted with CDI, as has been observed for other conditions such as atopy, obesity, and food allergies. However, more research is needed to understand the interactions between pets, owners, and their microbiota.

Indexed as

Clostridioides difficilemicrobiomepetsrecurrencezoonosis

Identifiers

PMID31976354
PMCPMC6969483
OpenAlexW2999973323

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.