Evidence map›Paper›PMID 31976330›Full record

ArticleBioMed research international2019

The Coumarin Derivative 5'-Hydroxy Auraptene Suppresses Osteoclast Differentiation via Inhibiting MAPK and c-Fos/NFATc1 Pathways.

Basem M Abdallah, Enas M Ali, Hany Elsawy, Gehan M Badr, Ashraf M Abdel-Moneim, Abdullah M Alzahrani

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Water Extract ofFoods (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Basem M AbdallahBiological Sciences Department, College of Science, King Faisal University, Hofuf, Saudi Arabia.ORCID https://orcid.org/0000-0003-0324-8055
Enas M AliBiological Sciences Department, College of Science, King Faisal University, Hofuf, Saudi Arabia.ORCID https://orcid.org/0000-0002-9794-1557
Hany ElsawyDepartment of Chemistry, Faculty of Science, King Faisal University, Hofuf, Saudi Arabia.ORCID https://orcid.org/0000-0001-8250-4023
Gehan M BadrBiological Sciences Department, College of Science, King Faisal University, Hofuf, Saudi Arabia.ORCID https://orcid.org/0000-0001-9629-2260
Ashraf M Abdel-MoneimBiological Sciences Department, College of Science, King Faisal University, Hofuf, Saudi Arabia.
Abdullah M AlzahraniBiological Sciences Department, College of Science, King Faisal University, Hofuf, Saudi Arabia.ORCID https://orcid.org/0000-0003-4372-4968
King Faisal University · SAAin Shams University · EGCairo University · EGTanta University · EGUniversity of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The phytochemical substances, coumarin derivatives, have demonstrated antiresorptive bone effects by suppressing osteoclast differentiation

Indexed as

AnimalsBone Marrow CellsCell DifferentiationCell ProliferationCell SurvivalCoumarinsDose-Response Relationship, DrugGene ExpressionLotusMaleMiceMice, Inbred C57BLMitogen-Activated Protein Kinase KinasesNFATC Transcription FactorsNF-kappa BOsteoclastsauraptencoumarinCoumarinsMitogen-Activated Protein Kinase KinasesNfatc1 protein, mouseNFATC Transcription FactorsNF-kappa BPlant ExtractsProto-Oncogene Proteins c-fosRANK LigandRNA, MessengerTnfsf11 protein, mouse

Identifiers

PMID31976330
PMCPMC6949687
OpenAlexW2997664288

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.