Evidence map›Paper›PMID 31976311›Full record

Trial reportCanadian journal of gastroenterology & hepatology2019

Intestinal Microbiome Changes in Fecal Microbiota Transplant (FMT)

Elvira Garza-González, Soraya Mendoza-Olazarán, Rayo Morfin-Otero, Andrea Ramírez-Fontes, Patricia Rodríguez-Zulueta, Samantha Flores-Treviño, Paola Bocanegra-Ibarias, Héctor Maldonado-Garza, Adrián Camacho-Ortiz

Open access · goldAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Canadian journal of gastroenterology & hepatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Comparative effectiveness of different therapies forThe Lancet regional health. Europe · 2025
    Article
  6. Review
  7. Article
  8. KOMB: K-core based de novo characterization of copy number variation in microbiomes.Computational and structural biotechnology journal · 2022
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Elvira Garza-GonzálezUniversidad Autónoma de Nuevo León, Facultad de Medicina, Hospital Universitario "Dr. José Eleuterio González", Monterrey, Nuevo León, Mexico.ORCID 0000-0001-5831-9661
Soraya Mendoza-OlazaránUniversidad Autónoma de Nuevo León, Facultad de Medicina, Hospital Universitario "Dr. José Eleuterio González", Monterrey, Nuevo León, Mexico.
Rayo Morfin-OteroUniversidad de Guadalajara, Hospital Civil de Guadalajara Fray Antonio Alcalde e Instituto de Patología Infecciosa y Experimental, Centro Universitario de Ciencias de la Salud, Guadalajara, Jalisco, Mexico.ORCID 0000-0001-9576-1950
Andrea Ramírez-FontesUniversidad Autónoma de Nuevo León, Facultad de Medicina, Hospital Universitario "Dr. José Eleuterio González", Monterrey, Nuevo León, Mexico.
Patricia Rodríguez-ZuluetaInfectious Diseases Service, Hospital General Manuel Gea González, Ciudad de Mexico, Mexico.
Samantha Flores-TreviñoUniversidad Autónoma de Nuevo León, Facultad de Medicina, Hospital Universitario "Dr. José Eleuterio González", Monterrey, Nuevo León, Mexico.
Paola Bocanegra-IbariasUniversidad Autónoma de Nuevo León, Facultad de Medicina, Hospital Universitario "Dr. José Eleuterio González", Monterrey, Nuevo León, Mexico.
Héctor Maldonado-GarzaUniversidad Autónoma de Nuevo León, Facultad de Medicina, Hospital Universitario "Dr. José Eleuterio González", Monterrey, Nuevo León, Mexico.
Adrián Camacho-OrtizUniversidad Autónoma de Nuevo León, Facultad de Medicina, Hospital Universitario "Dr. José Eleuterio González", Monterrey, Nuevo León, Mexico.ORCID 0000-0002-8044-0094
Universidad Autónoma de Nuevo León · MXHospital General Dr. Manuel Gea Gonzalez · MXUniversidad de Guadalajara · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: In this study, we conducted a comparative study to explore the differences in therapeutic efficacy and intestinal microbiome of fecal microbiota transplant (FMT) Methods: We designed a double-blinded randomized comparative two-arm pilot multicenter study to assess the efficacy and impact in the intestinal microbiome of standard capsules of FMT Results: We included 21 patients (13 in the FMT group and 8 in the FMT-L group). Overall, both groups had a reduction in bowel movements per day, from 8.6 to 3.2 in the first 48 h (62.7% reduction, Conclusion: Fecal microbiota transplant by capsules was clinically and genomically similar between traditional FMT and enriched FMT with

Indexed as

Clostridioides difficileGastrointestinal MicrobiomeLactobacillusAdolescentAdultAgedAged, 80 and overDouble-Blind MethodEnterocolitis, PseudomembranousFecal Microbiota TransplantationFecesFemaleHumansMaleMiddle AgedPilot ProjectsRNA, Ribosomal, 16S

Identifiers

PMID31976311
PMCPMC6955117
OpenAlexW2997079353

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.