Evidence map›Paper›PMID 31976310›Full record

ArticleCanadian journal of gastroenterology & hepatology2019

Deficiency of Dietary Fiber in

Sathish Sivaprakasam, Pramodh K Ganapathy, Mohd Omar Faruk Sikder, Moamen Elmassry, Sabarish Ramachandran, Kameswara Rao Kottapalli, Vadivel Ganapathy

Open access · goldAbstract read
In one paragraph

Article in Canadian journal of gastroenterology & hepatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sathish SivaprakasamDepartment of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.ORCID 0000-0002-9230-0144
Pramodh K GanapathyWashington University School of Medicine, St. Louis, MO, USA.
Mohd Omar Faruk SikderDepartment of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.ORCID 0000-0003-1931-095X
Moamen ElmassryDepartment of Biological Sciences, Texas Tech University, Lubbock, TX 79409, USA.
Sabarish RamachandranDepartment of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.
Kameswara Rao KottapalliDepartment of Biotechnology, Genomic Center, Texas Tech University, Lubbock, TX 79409, USA.
Vadivel GanapathyDepartment of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.ORCID 0000-0003-0799-6018
Texas Tech University · USWashington University in St. Louis · US

Funding

SLC5A8 is a conditional tumor suppressor in colon linked to dietary fiber contentR01CA190710 · NCI · TEXAS TECH UNIVERSITY HEALTH SCIS CENTER · PI GANAPATHY, VADIVEL · 2015 to 2019
$1.8M
NCI NIH HHS R01 CA190710
6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) is characterized by chronic inflammation in the intestinal tract due to disruption of the symbiotic relationship between the host immune system and microbiota. Various factors alter the gut microbiota which lead to dysbiosis; in particular, diet and dietary fibers constitute important determinants. Dietary fiber protects against IBD; bacteria ferment these dietary fibers in colon and generate short-chain fatty acids (SCFAs), which mediate the anti-inflammatory actions of dietary fibers. SLC5A8 is a high-affinity transporter in the apical membrane of colonic epithelium which mediates the entry of SCFAs from the lumen into cells in Na

Indexed as

AnimalsColitisColonDietDietary FiberDysbiosisInflammationIntestinal MucosaMiceMonocarboxylic Acid TransportersTranscriptomeDietary FiberMonocarboxylic Acid TransportersSlc5a8 protein, mouse

Identifiers

PMID31976310
PMCPMC6949682
OpenAlexW2997934674

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.