ArticleWorld journal of clinical oncology2020
Predictors of distant metastasis in acinic cell carcinoma of the parotid gland.
Article in World journal of clinical oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- A Case of Acinic Cell Carcinoma Metastasizing to the Heart.Head and neck pathology · 2025Article
- Role of stereotactic radiosurgery for recurrent skull base acinic cell carcinoma: illustrative case.Journal of neurosurgery. Case lessons · 2024Article
- Chaotic transformation of parotid acinic cell carcinoma to metastatic dedifferentiated high-grade pathology - A rare case with clinical and emotional challenge.International journal of surgery case reports · 2023Article
- Head and Neck Acinic Cell Carcinoma: A New Grading System Proposal and Diagnostic Utility of NR4A3 Immunohistochemistry.The American journal of surgical pathology · 2022Article
- A Rare Case of Brain Metastasis from Dedifferentiated Acinic Cell Carcinoma of the Parotid Gland and Review of the Literature.Iranian journal of pathology · 2022Article
- Acinic cell carcinoma of the parotid gland: from pathogenesis to management: a literature review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2020Review
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAiCC is a primarily indolent disease process. Our aim with this study is to determine characteristics consistent with rapidly progressive AiCC of the parotid gland.
aimTo report on patients with metastatic lung disease from AiCC and potential correlative factors.
methodsSingle-institution retrospective review of patients treated at the University of Michigan between 2000 and 2017. Univariate analyses were performed.
resultsA total of 55 patients were identified. There were 6 patients (10.9%) with primary AiCC of the parotid gland who developed lung metastases. The mean age at diagnosis for patients with lung metastases was 57.8 years of age, in comparison to 40.2 years for those without metastases (
conclusionAiCC of the parotid gland is viewed as a low-grade neoplasm with good curative outcomes and low likelihood of metastasis. With metastasis, however, it does exhibit a tendency to spread to the lungs. These patients thereby comprise a unique and understudied patient population. In this retrospective study, factors that have been shown to be statistically significant in association with worse disease-free survival and overall survival include presence of gross facial nerve invasion, higher T-classification, and high-grade disease.
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