Evidence map›Paper›PMID 31976086›Full record

ArticleJournal of ophthalmology2019

Fluorescein Angiographic Findings of Peripheral Retinal Vasculature after Intravitreal Conbercept versus Ranibizumab for Retinopathy of Prematurity.

Enzhong Jin, Hong Yin, Yufei Gui, Juan Chen, Jian Zhang, Jianhong Liang, Xiao-Xin Li, Mingwei Zhao

Open access · goldAbstract read
In one paragraph

Article in Journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Repeated intravitreal ranibizumab for reactivated retinopathy of prematurity after intravitreal ranibizumab monotherapy: vascular development analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Enzhong JinDepartment of Ophthalmology, Ophthalmology & Optometry Center, Peking University People's Hospital, Beijing, China.
Hong YinDepartment of Ophthalmology, Ophthalmology & Optometry Center, Peking University People's Hospital, Beijing, China.ORCID https://orcid.org/0000-0002-6945-1518
Yufei GuiDepartment of Ophthalmology, Ophthalmology & Optometry Center, Peking University People's Hospital, Beijing, China.
Juan ChenDepartment of Ophthalmology, Beijing Jingmei Group General Hospital, Beijing, China.
Jian ZhangDepartment of Ophthalmology, Ophthalmology & Optometry Center, Peking University People's Hospital, Beijing, China.
Jianhong LiangDepartment of Ophthalmology, Ophthalmology & Optometry Center, Peking University People's Hospital, Beijing, China.ORCID https://orcid.org/0000-0002-6198-4125
Xiao-Xin LiDepartment of Ophthalmology, Ophthalmology & Optometry Center, Peking University People's Hospital, Beijing, China.ORCID https://orcid.org/0000-0002-5161-9458
Mingwei ZhaoDepartment of Ophthalmology, Ophthalmology & Optometry Center, Peking University People's Hospital, Beijing, China.ORCID https://orcid.org/0000-0003-1370-6275
Peking University · CNBeijing Tongren Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate angiographic findings of peripheral retina vasculature in retinopathy of prematurity (ROP) neonates who received intravitreal conbercept (IVC) or ranibizumab (IVR).

methodsFluorescein angiography (FA) findings were retrospectively evaluated for ROP neonates who received IVC or IVR. Outcome measures included peripheral avascular zone, vascular leakage, vascular blunting, vascular loops, vascular dilatation, arteriovenous shunt, and capillary dropout.

resultsFifty-four eyes (28 patients) with ROP were included. Twenty-nine eyes (15 patients) received IVC, and 25 eyes (13 patients) received IVR. For infants of the IVC group, the mean gestational age, birth weight, and postmenstrual age (PMA) at the initial treatment were 28.96 ± 2.36 weeks, 1168.8 ± 344.5 g, and 41.22 ± 4.39 weeks, respectively. For the IVR group, they were 28.83 ± 2.34 weeks, 1255.0 ± 356.9 g, and 39.42 ± 2.77 weeks, respectively (

conclusionNo significant difference can be observed between the IVC group and IVR group for peripheral vascular structure anomalies with FA evidence. FA studies should be considered to assess the status of the peripheral retinal vasculature to determine therapeutic outcomes and potential functional outcomes.

Identifiers

PMID31976086
PMCPMC6955114
OpenAlexW2998318379

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.