Evidence map›Paper›PMID 31976081›Full record

ArticleMultiple sclerosis journal - experimental, translational and clinical

Factors affecting MS patients' health-related quality of life and measurement challenges in Lebanon and the MENA region.

Natali Farran, Batoul R Safieddine, Mariam Bayram, Tracy Abi Hanna, Joelle Massouh, Mona AlKhawaja, Hani Tamim, Hala Darwish

Open access · goldAbstract read
In one paragraph

Article in Multiple sclerosis journal - experimental, translational and clinical. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Cultural Adaptation and Validation of the CALMS Questionnaire in an Arabic-Speaking MS Population.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2026
    Article
  2. Article
  3. Quality of life and access to treatment for patients with multiple sclerosis during economic crisis: the Lebanese experience.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
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  15. Multiple sclerosis in the Middle East and North Africa region.Multiple sclerosis journal - experimental, translational and clinical
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Natali Farran
Batoul R Safieddine
Mariam BayramHariri School of Nursing, American University of Beirut, Lebanon.
Tracy Abi Hanna
Joelle MassouhNehme and Therese Tohme Multiple Sclerosis Center, American University of Beirut Medical Center, Lebanon.
Mona AlKhawajaNeurology Department, King Faisal Specialist Hospital and Research Center, Saudi Arabia.
Hani TamimClinical Research Institute, American University of Beirut Medical Center, Lebanon.
Hala DarwishHariri School of Nursing, American University of Beirut, Lebanon.ORCID https://orcid.org/0000-0001-5744-6466
American University of Beirut Medical Center · LBAmerican University of Beirut · LBKing Faisal Specialist Hospital & Research Centre · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the Middle East and North Africa (MENA) region, few studies explored the quality of life of multiple sclerosis patients and the factors affecting it.

objectiveThe objective of this study was to explore studies on multiple sclerosis quality of life in the MENA area through a comprehensive literature review. To validate the Multiple sclerosis international Quality of Life (MusiQoL) and Modified Fatigue Impact Scale (MFIS) in Arabic, and investigate the impact of sociodemographic and clinical variables of Lebanese multiple sclerosis patients on quality of life.

methodsAs part of an ongoing observational prospective research study, data from 663 stable multiple sclerosis patients were analysed.

resultsIn Lebanese multiple sclerosis patients, the Arabic MusiQoL and MFIS seem to be accurate and valid tools with high reliability coefficients and confirmatory factor analytic indices. Variables such as age and disease type predicted multiple sclerosis quality of life, yet were significantly affected by psychosocial fatigue. The influence of sociodemographic and clinical variables on quality of life dimensions varied. Being a woman with multiple sclerosis, receiving medications and experiencing physical fatigue worsens the psychological wellbeing quality of life dimension.

conclusionSeveral sociodemographic and clinical variables predicted the health-related quality of life dimensions of multiple sclerosis patients in MENA. Further in-depth investigation to guide more targeted clinical management is recommended. We encourage using validated multidimensional tools to measure quality of life in MENA such as the Arabic MusiQoL.

Indexed as

fatigueLebanonMENAMultiple sclerosisquality of life

Identifiers

PMID31976081
PMCPMC6956607
OpenAlexW2999939076

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.