Evidence map›Paper›PMID 31976023›Full record

ArticleDisease markers2019

Proximal Gastrectomy versus Total Gastrectomy for Siewert Type II Adenocarcinoma of the Esophagogastric Junction: A Comprehensive Analysis of Data from the SEER Registry.

Kaixuan Zhu, Yingying Xu, Jiaxin Fu, Farah Abdidahir Mohamud, Zongkui Duan, Siyuan Tan, Zekun Zhao, Ping Chen, Liang Zong

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Disease markers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Kaixuan ZhuDepartment of General Surgery, Northern Jiangsu People's Hospital, Clinical Medical College, Yangzhou University, Jiangsu Province, China.
Yingying XuDepartment of General Surgery, Yizheng People's Hospital, Clinical Medical College, Yangzhou University, Jiangsu Province, China.
Jiaxin FuDepartment of General Surgery, Northern Jiangsu People's Hospital, Clinical Medical College, Yangzhou University, Jiangsu Province, China.
Farah Abdidahir MohamudDepartment of General Surgery, Northern Jiangsu People's Hospital, Clinical Medical College, Yangzhou University, Jiangsu Province, China.
Zongkui DuanDepartment of General Surgery, Northern Jiangsu People's Hospital, Clinical Medical College, Yangzhou University, Jiangsu Province, China.
Siyuan TanDepartment of General Surgery, Northern Jiangsu People's Hospital, Clinical Medical College, Yangzhou University, Jiangsu Province, China.
Zekun ZhaoDepartment of General Surgery, Tongji Hospital, Medical School of Tongji University, Shanghai, China.ORCID https://orcid.org/0000-0001-8913-7094
Ping ChenDepartment of General Surgery, Northern Jiangsu People's Hospital, Clinical Medical College, Yangzhou University, Jiangsu Province, China.
Liang ZongDepartment of General Surgery, Northern Jiangsu People's Hospital, Clinical Medical College, Yangzhou University, Jiangsu Province, China.ORCID https://orcid.org/0000-0003-4139-4571
Northern Jiangsu People's Hospital · CNTongji University · CNYangzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo determine the ideal surgical approach (total gastrectomy (TG) vs. proximal gastrectomy (PG)) for Siewert type II adenocarcinoma of the esophagogastric junction (AEG), we searched and analyzed the Surveillance, Epidemiology, and End Results (SEER) data.

methodsPatients with Siewert type II AEG treated by TG or PG were identified from the 2004-2014 SEER dataset. We obtained the patients' overall survival (OS) and cancer-specific survival (CSS) and stratified the patients by surgical approach. We performed a propensity score 1 : 1 matching (PSM) analysis and a univariate and multivariate Cox proportional hazards model.

resultsA total of 2,217 patients with 6th AJCC stage IA-IIIB Siewert type II AEG was examined: 1,584 patients (71.4%) underwent PG, and 633 patients (28.6%) underwent TG. The follow-up time was 1-131 months. OS favored total gastrectomy before the PSM analysis (

conclusionsPG showed an equivalent survival benefit to TG in both the early and locally advanced stages of Siewert type II AEG. For elderly patients, PG is strongly recommended because of its clearer OS benefit compared to TG.

Indexed as

AdenocarcinomaEsophageal NeoplasmsEsophagogastric JunctionFemaleGastrectomyHumansLymphatic MetastasisMalePropensity ScoreProportional Hazards ModelsRetrospective StudiesSEER ProgramStomach NeoplasmsTreatment Outcome

Identifiers

PMID31976023
PMCPMC6955131
OpenAlexW2997677113

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.