ArticleeLife2020
Damage to the right insula disrupts the perception of affective touch.
Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The trial behind it
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Who cites it
32 citing papers in PubMed, 78 citations in OpenAlex.
- Analysis of correlation between structural changes and functional response in post-stroke motor recovery after cM1 LF-rTMS: an exploratory randomized trial.Scientific reports · 2026Trial
- Widespread Pressure Delivered by a Weighted Blanket Reduces Chronic Pain: A Randomized Controlled Trial.The journal of pain · 2022Trial
- Through Massage to the Brain-Neuronal and Neuroplastic Mechanisms of Massage Based on Various Neuroimaging Techniques (EEG, fMRI, and fNIRS).Journal of clinical medicine · 2026Review
- Dynamic functional adaptations during touch observation in autism: connectivity strength is linked to attitudes towards social touch and social responsiveness.Molecular autism · 2025Article
- Does affective touch buffer emotional distress? Insights from subjective and physiological indices.Social cognitive and affective neuroscience · 2025Article
- Linking heartbeats with the cortical network dynamics involved in self-social touch distinction.Communications biology · 2025Article
- Touching soft materials slows affective visual processing.Frontiers in psychology · 2025Article
- Working memory related brain-behavior associations in the context of socioeconomic and psychosocial deprivation.Cortex; a journal devoted to the study of the nervous system and behavior · 2024Article
- Neurophysiological evidence of motor contribution to vicarious affective touch.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Pupil dilation responds to the intrinsic social characteristics of affective touch.Scientific reports · 2024Article
- Subcortical contributions to the sense of body ownership.Brain : a journal of neurology · 2024Article
- MDMA modulates human sensorimotor cortical pathways during gentle touch.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- To touch or to be touched? comparing appraisal of vicarious execution and reception of interpersonal touch.PloS one · 2024Article
- The Role of the Skin in Interoception: A Neglected Organ?Perspectives on psychological science : a journal of the Association for Psychological Science · 2023Article
- Motor awareness: a model based on neurological syndromes.Brain structure & function · 2022Review
- Article
- A longitudinal investigation of GABA, glutamate, and glutamine across the insula during antipsychotic treatment of first-episode schizophrenia.Schizophrenia research · 2022Article
- Brain-heart interactions in the neurobiology of consciousness.Current research in neurobiology · 2022Review
- Hearing, touching, and multisensory integration during mate choice.Frontiers in neural circuits · 2022Review
- The brain-body disconnect: A somatic sensory basis for trauma-related disorders.Frontiers in neuroscience · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 7 institutions in 5 countries.
Funding
Abstract
Specific, peripheral C-tactile afferents contribute to the perception of tactile pleasure, but the brain areas involved in their processing remain debated. We report the first human lesion study on the perception of C-tactile touch in right hemisphere stroke patients (N = 59), revealing that right posterior and anterior insula lesions reduce tactile, contralateral and ipsilateral pleasantness sensitivity, respectively. These findings corroborate previous imaging studies regarding the role of the posterior insula in the perception of affective touch. However, our findings about the crucial role of the anterior insula for ipsilateral affective touch perception open new avenues of enquiry regarding the cortical organization of this tactile system.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.