Evidence map›Paper›PMID 31975432›Full record

ArticleMagnetic resonance in medicine2020

Feasibility of a sub-3-minute imaging strategy for ungated quiescent interval slice-selective MRA of the extracranial carotid arteries using radial k-space sampling and deep learning-based image processing.

Ioannis Koktzoglou, Rong Huang, Archie L Ong, Pascale J Aouad, Emily A Aherne, Robert R Edelman

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ioannis KoktzoglouDepartment of Radiology, NorthShore University HealthSystem, Evanston, Illinois.ORCID 0000-0001-9335-2010
Rong HuangDepartment of Radiology, NorthShore University HealthSystem, Evanston, Illinois.
Archie L OngPritzker School of Medicine, University of Chicago, Chicago, Illinois.
Pascale J AouadDepartment of Radiology, NorthShore University HealthSystem, Evanston, Illinois.
Emily A AherneDepartment of Radiology, NorthShore University HealthSystem, Evanston, Illinois.
Robert R EdelmanDepartment of Radiology, NorthShore University HealthSystem, Evanston, Illinois.ORCID 0000-0002-0013-8822
NorthShore University HealthSystem · USNorthwestern University · US

Funding

Rapid Real-Time MR Angiography of Suspected StrokeR01EB027475 · NIBIB · ENDEAVOR HEALTH CLINICAL OPERATIONS · PI KOKTZOGLOU, IOANNIS · 2018 to 2021
$1.9M
NIBIB NIH HHS R01 EB027475
6 · The paper itself

Abstract

purposeTo develop and test the feasibility of a sub-3-minute imaging strategy for non-contrast evaluation of the extracranial carotid arteries using ungated quiescent interval slice-selective (QISS) MRA, combining single-shot radial sampling with deep neural network-based image processing to optimize image quality.

methodsThe extracranial carotid arteries of 12 human subjects were imaged at 3 T using ungated QISS MRA. In 7 healthy volunteers, the effects of radial and Cartesian k-space sampling, single-shot and multishot image acquisition (1.1-3.3 seconds/slice, 141-423 seconds/volume), and deep learning-based image processing were evaluated using segmental image quality scoring, arterial temporal SNR, arterial-to-background contrast and apparent contrast-to-noise ratio, and structural similarity index. Comparison of deep learning-based image processing was made with block matching and 3D filtering denoising.

resultsCompared with Cartesian sampling, radial k-space sampling increased arterial temporal SNR 107% (P < .001) and improved image quality during 1-shot imaging (P < .05). The carotid arteries were depicted with similar image quality on the rapid 1-shot and much lengthier 3-shot radial QISS protocols (P = not significant), which was corroborated in patient studies. Deep learning-based image processing outperformed block matching and 3D filtering denoising in terms of structural similarity index (P < .001). Compared with original QISS source images, deep learning image processing provided 24% and 195% increases in arterial-to-background contrast (P < .001) and apparent contrast-to-noise ratio (P < .001), and provided source images that were preferred by radiologists (P < .001).

conclusionRapid, sub-3-minute evaluation of the extracranial carotid arteries is feasible with ungated single-shot radial QISS, and benefits from the use of deep learning-based image processing to enhance source image quality.

Indexed as

Deep LearningCarotid ArteriesFeasibility StudiesHumansImage Interpretation, Computer-AssistedMagnetic Resonance Angiographycarotiddeep learningMRAQISSradial

Identifiers

PMID31975432
PMCPMC7180090
OpenAlexW3001278077

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.