ArticleMethods in molecular biology (Clifton, N.J.)2020
Exploring Population Structure with Admixture Models and Principal Component Analysis.
Article in Methods in molecular biology (Clifton, N.J.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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Who cites it
48 citing papers in PubMed.
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- Age-stratified genomic analyses reveal population-specific genetic determinants of exceptional longevity in Taiwan.GeroScience · 2026Article
- Cross-species transferability and genetic diversity analysis in Linum species using microsatellite markers.Scientific reports · 2026Article
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- An exploratory exome-wide machine learning analysis identifies candidate host gene signatures associated with Long COVID in a large admixed Brazilian cohort.Frontiers in medicine · 2026Article
- Genetic diversity and population structure ofFrontiers in plant science · 2026Article
- Genetic differentiation in domesticated black soldier fly (Hermetia illucens) populations.BMC biology · 2025Article
- Population Genomics of Incipient Allochronic Divergence in the Pine Processionary Moth.Molecular ecology · 2025Article
- Emanating candidate genes responsible for fruit quality traits in citrus through GBS-based genome wide association studies.BMC genomics · 2025Article
- Analysis of genetic diversity among wild soybean (Glycine soja) from Hengshui Lake in Hebei Province, China.BMC genomic data · 2025Article
- Article
- Genetic diversity and population structure of ALS-resistant Amaranthus hybridus across Brazil's primary soybean-growing regions.Pest management science · 2025Article
- Titin-Truncating variants predispose to dilated cardiomyopathy in populations genetically similar to african and european reference populations.PLoS genetics · 2025Article
- Multiple Origins or Widespread Gene Flow in Agricultural Fields? Regional Population Genomics of Herbicide Resistance in Bromus tectorum.Molecular ecology · 2025Article
- The genomic legacy of selectively breeding rhesus macaques for HIV/AIDS-related research.bioRxiv : the preprint server for biology · 2025Article
- Adaptive genomic signatures of globally invasive populations of the yellow fever mosquito Aedes aegypti.Nature ecology & evolution · 2025Article
- Experience using conventional compared to ancestry-based population descriptors in clinical genomics laboratories.American journal of human genetics · 2025Review
- Genome-wide association studies reveal potential candidate genes associated with amino acid in tea plants.PeerJ · 2025Article
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Authors and funding
4 authors.
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Abstract
Population structure is a commonplace feature of genetic variation data, and it has importance in numerous application areas, including evolutionary genetics, conservation genetics, and human genetics. Understanding the structure in a sample is necessary before more sophisticated analyses are undertaken. Here we provide a protocol for running principal component analysis (PCA) and admixture proportion inference-two of the most commonly used approaches in describing population structure. Along with hands-on examples with CEPH-Human Genome Diversity Panel and pragmatic caveats, readers will learn to analyze and visualize population structure on their own data.
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