Evidence map›Paper›PMID 31974933›Full record

ReviewNeurochemical research2020

Glial Factors Regulating White Matter Development and Pathologies of the Cerebellum.

Miren Revuelta, Till Scheuer, Li-Jin Chew, Thomas Schmitz

Abstract readReview
In one paragraph

Review in Neurochemical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Glial Cells and Aging: From the CNS to the Cerebellum.International journal of molecular sciences · 2025
    Review
  3. Article
  4. The progress of the microbe-gut-brain axis in sepsis-associated encephalopathy.Frontiers in cellular and infection microbiology · 2025
    Review
  5. Article
  6. The Neuroimmune System and the Cerebellum.Cerebellum (London, England) · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Miren RevueltaDepartment for Neonatology, Charité University Medical Center, Augustenburger Platz 1, Mittelallee 9, 3353, Berlin, Germany.
Till ScheuerDepartment for Neonatology, Charité University Medical Center, Augustenburger Platz 1, Mittelallee 9, 3353, Berlin, Germany.
Li-Jin ChewCenter for Neuroscience Research, Children's Research Institute, Children's National Medical Center, Washington, DC, USA.
Thomas SchmitzDepartment for Neonatology, Charité University Medical Center, Augustenburger Platz 1, Mittelallee 9, 3353, Berlin, Germany. thomas.schmitz@charite.de.ORCID http://orcid.org/0000-0001-8193-8970

Funding

Deutsche Forschungsgemeinschaft SCHE2078/2-1Deutsche Forschungsgemeinschaft SCHM3007/3-2Institute of Education, University and Research of the Basque Government POS_2017_1_0095
6 · The paper itself

Abstract

The cerebellum is a brain region that undergoes extremely dynamic growth during perinatal and postnatal development which is regulated by the proper interaction between glial cells and neurons with a complex concert of growth factors, chemokines, cytokines, neurotransmitters and transcriptions factors. The relevance of cerebellar functions for not only motor performance but also for cognition, emotion, memory and attention is increasingly being recognized and acknowledged. Since perturbed circuitry of cerebro-cerebellar trajectories can play a role in many central nervous system pathologies and thereby contribute to neurological symptoms in distinct neurodevelopmental and neurodegenerative diseases, is it the aim with this mini-review to highlight the pathways of glia-glia interplay being involved. The designs of future treatment strategies may hence be targeted to molecular pathways also playing a role in development and disease of the cerebellum.

Indexed as

AnimalsCerebellumHumansNeurogliaSignal TransductionWhite MatterCerebellumDevelopmentGliaPathologiesTherapy

Identifiers

PMID31974933
PMCPMC7058568

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.