SynthesisIntensive care medicine2020
Rate and risk factors for rehospitalisation in sepsis survivors: systematic review and meta-analysis.
Synthesis in Intensive care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
77 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Long-term mortality in pediatric sepsis: a systematic review and meta-analysis.Annals of medicine · 2026Pooled it
- Risk factors for sepsis: a systematic review and meta-analysis.Frontiers in public health · 2026Pooled it
- Healthcare costs after sepsis: a systematic review.Critical care (London, England) · 2025Pooled it
- Pre-implementation planning for a sepsis intervention in a large learning health system: a qualitative study.BMC health services research · 2024Trial
- Post-Sepsis Outcomes: Risk Factors for 90-Day Mortality and Infection Site-Pathogen Similarity in Recurrent Sepsis.Turkish journal of anaesthesiology and reanimation · 2026Article
- Strategies to address implementation barriers in sepsis survivors' care transitions to home health and outpatient care: a multi-site, type 1 hybrid implementation study.BMC health services research · 2026Article
- Immune responses and immunomodulation in sepsis: a call for identifying treatable mechanisms.Intensive care medicine · 2026Article
- Trajectories of sepsis survivors in Australia: A scoping review.Journal of the Intensive Care Society · 2026Article
- Temporal Trends in the Chronobiology and Epidemiology of Sepsis Admissions over 21 Years: A Nationwide Study in Northwestern Spain.Antibiotics (Basel, Switzerland) · 2026Article
- Patterns and predictors of readmission among sepsis survivors in a tertiary emergency department in Ethiopia.IJID regions · 2026Article
- The risk of cardiovascular events following community-acquired sepsis: a nationwide cohort study in Sweden.Epidemiology and infection · 2026Article
- Risk Factors for Adverse Outcomes in Cancer Patients With Sepsis.Journal of clinical medicine research · 2026Article
- Article
- Transitional care after hospitalization for sepsis in Germany- results from the population-based AVENIR cohort study.Infection · 2025Article
- Multi‑omics reveal neutrophil heterogeneity in sepsis (Review).International journal of molecular medicine · 2025Review
- Top 10 research priorities for sepsis research determined by patients, carers and clinicians.Anaesthesia · 2025Article
- Emergency Department Reconsultations After a Secondary Prevention Bundle for Medication-Related Problems: A Retrospective Cohort Study.Journal of clinical medicine · 2025Article
- Patient-level barriers, related facilitators, and proposed strategies for timely home health care and outpatient appointments for sepsis survivors: Perspectives from healthcare system and home health care informants.Patient education and counseling · 2025Article
- Long-term cardiovascular outcomes and risk factors in adult sepsis survivors: a systematic review and meta-analysis.World journal of emergency medicine · 2025Review
- Progression of Kidney Fibrosis after Sepsis: Underestimated Role of Resident Macrophages and Recruited Monocytes.Journal of the American Society of Nephrology : JASN · 2025Review
17 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
purposeSepsis survivors have a higher risk of rehospitalisation and of long-term mortality. We assessed the rate, diagnosis, and independent predictors for rehospitalisation in adult sepsis survivors.
methodsWe searched for non-randomized studies and randomized clinical trials in MEDLINE, Cochrane Library, Web of Science, and EMBASE (OVID interface, 1992-October 2019). The search strategy used controlled vocabulary terms and text words for sepsis and hospital readmission, limited to humans, and English language. Two authors independently selected studies and extracted data using predefined criteria and data extraction forms.
resultsThe literature search identified 12,544 records. Among 56 studies (36 full and 20 conference abstracts) that met our inclusion criteria, all were non-randomised studies. Studies most often report 30-day rehospitalisation rate (mean 21.4%, 95% confidence interval [CI] 17.6-25.4%; N = 36 studies reporting 6,729,617 patients). The mean (95%CI) rehospitalisation rates increased from 9.3% (8.3-10.3%) by 7 days to 39.0% (22.0-59.4%) by 365 days. Infection was the most common rehospitalisation diagnosis. Risk factors that increased the rehospitalisation risk in sepsis survivors were generic characteristics such as older age, male, comorbidities, non-elective admissions, hospitalisation prior to index sepsis admission, and sepsis characteristics such as infection and illness severity, with hospital characteristics showing inconsistent associations. The overall certainty of evidence was moderate for rehospitalisation rates and low for risk factors.
conclusionsRehospitalisation events are common in sepsis survivors, with one in five rehospitalisation events occurring within 30 days of hospital discharge following an index sepsis admission. The generic and sepsis-specific characteristics at index sepsis admission are commonly reported risk factors for rehospitalisation. REGISTRATION: PROSPERO CRD 42016039257, registered on 14-06-2016.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.