Evidence map›Paper›PMID 31974916›Full record

ArticleDigestive diseases and sciences2020

Geographically Focused Collocated Hepatitis C Screening and Treatment in Los Angeles's Skid Row.

Trista Marie Benitez, Shannon Melania Fernando, Christina Amini, Sammy Saab

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In one paragraph

Article in Digestive diseases and sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

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  5. Current status of disparity in liver disease.World journal of hepatology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Trista Marie BenitezLos Angeles Christian Health Centers, Los Angeles, CA, USA.
Shannon Melania FernandoLos Angeles Christian Health Centers, Los Angeles, CA, USA.
Christina AminiLos Angeles Christian Health Centers, Los Angeles, CA, USA.
Sammy SaabDepartments of Medicine, Nursing, and Surgery, University of California at Los Angeles, Los Angeles, CA, USA. SSaab@mednet.ucla.edu.
University of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe inequitable prevalence of hepatitis C (HCV) in the homeless is a clinical and public health concern. Prior research estimates, at least one-quarter of homeless persons have been infected with HCV, yet linkage to care and treatment uptake remains marginal.

aimTo evaluate the feasibility of treating HCV in a homeless population.

methodsRetrospective study of homeless individuals treated for HCV. Demographic information including risk factors was collected. Univariate analyses were performed. The proportion of patients linked to care and sustained viral response at 12 weeks post-treatment (SVR12) was measured.

resultsDuring the study period, 6767 individuals were screened for HCV. A total of 769 (11.4%) were found to have detectable HCV antibodies. Of the individuals with detectable HCV antibodies, 443 (57.6%) were viremic. Of the 443 viremic patients, 375 (84.7%) were linked to care. Among them, 59 patients began antiviral treatment and 95% (56/59) completed the course of therapy. The ITT was 83.1% (49/59), and the per-protocol virologic cure rate was 100% (49/49).

conclusionThe favorable linkage to care and cure outcomes in our study suggests that homeless persons may be more likely to engage in HCV screening and treatment when these services are located in the community for their use. Our study further lends support to the efficacy of care coordination programs to encourage movement through the HCV care continuum in vulnerable populations.

Indexed as

Delivery of Health Care, IntegratedDiagnostic Screening ProgramsHealthcare DisparitiesHealth Status DisparitiesIll-Housed PersonsAdultAntiviral AgentsFeasibility StudiesFemaleHealth Services AccessibilityHepatitis C, ChronicHumansLos AngelesMaleMedically Underserved AreaMiddle AgedAntiviral AgentsComplianceHepatitis CScreening

Identifiers

PMID31974916
OpenAlexW3001979220

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.