ReviewFrontiers of medicine2020
Eliminating mother-to-child transmission of HBV: progress and challenges in China.
Review in Frontiers of medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Estimates of the global prevalence of occult hepatitis B virus infection in population under 18 years old: a systematic review and meta-analysis.Hepatology international · 2025Pooled it
- Hepatitis B Infection Among Pregnant Women in China: A Systematic Review and Meta-Analysis.Frontiers in public health · 2022Pooled it
- The impact of different IPV-OPV sequential immunization programs on hepatitis A and hepatitis B vaccine efficacy.Human vaccines & immunotherapeutics · 2022Trial
- Article
- Spatial and Temporal Disparities in Timely Hepatitis B Birth-Dose Vaccination in Chongqing, China, 2016-2025.Vaccines · 2026Article
- A Rare Pediatric Presentation: Concurrent Detection of All Five Hepatitis B Virus (HBV) Serological Markers.Journal of clinical medicine · 2026Article
- Factors of post-vaccination serological testing coverage among hepatitis B-exposed children in Fujian, China: a population-based cohort study (2021-2023).Frontiers in public health · 2026Article
- Low HBV replication does not aggravate disease progression in patients with superinfection with HEV.Scientific reports · 2025Article
- Knowledge, perceptions, and health education needs regarding hepatitis B virus among HBsAg-positive pregnant women in Taiyuan, China: a cross-sectional study.BMC public health · 2025Article
- Mother-to-child transmission of hepatitis B virus, its associated risk factors, and the adoption of maternal antiviral therapy in eastern China: a retrospective cohort study.BMC infectious diseases · 2025Article
- Analysis of HBV infection characteristics and OBI prevalence in pregnant women: a focus on HBcAb + alone or in combination with HBeAb + subgroups in Northwest China.BMC infectious diseases · 2025Article
- A study on pregenomic RNA and factors in the pregnant and postpartum women with chronic HBV infection based on real world.Frontiers in cellular and infection microbiology · 2025Article
- Health economic evaluation of newborn hepatitis B immunization prevention strategies in Ningbo: a Markov modeling study.Frontiers in public health · 2025Article
- Results of mother-to-child transmission in hepatitis B-positive mothers who underwent amniocentesis.BMC infectious diseases · 2024Article
- [Epidemiological analysis of the current prevalence of hepatitis B virus infection among pregnant and postpartum women in China from 2021 to 2023].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2024Article
- PgRNA closely correlates to cytokine profile in HBeAg-positive pregnant women undergoing prophylactic antiviral intervention.Frontiers in immunology · 2024Article
- Secular Trends of Liver Cancer Mortality and Years of Life Lost in Wuhan, China 2010-2019.Current oncology (Toronto, Ont.) · 2023Article
- Article
- Evaluation of factors associated the expression of anti-HBs in children in Hunan Province, China.BMC pediatrics · 2022Article
- Modeling long-term persistence after 8 years of hepatitis B booster vaccination in 5- to 15-year-old children.Human vaccines & immunotherapeutics · 2022Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
China has the world's largest burden of hepatitis B virus (HBV) infection, but the country has made considerable progress in preventing its mother-to-child transmission (MTCT) in the past three decades. This feat is made possible due to the high coverage of birth-dose hepatitis B vaccine (HepB, > 95%), hepatitis B surface antigen (HBsAg) screening for pregnant women ( > 99%), and hepatitis B immunoglobulin plus HepB for newborns whose mothers are HBsAg positive ( > 99%). Studies on the optimal antiviral treatment regimen for pregnant women with high HBV-DNA load have also been conducted. However, China still faces challenges in eliminating MTCT of HBV. The overall HBsAg prevalence among pregnant women is considered an intermediate endemic. The prevalence of HBsAg among pregnant women from remote, rural, or ethnic minority areas is higher than that of the national level because of limited health resources and public health education for HBV. The coverage for maternal and child healthcare and immunization services should be improved, especially in western regions. Integration of current services to prevent MTCTof HBV with other relevant health services can increase the acceptability, efficiency, and coverage of these services, particularly in remote areas and ethnic minority areas. By doing so, progress toward key milestones and targets to eliminate hepatitis B as the main public health threat by 2030 can be achieved.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.