Evidence map›Paper›PMID 31974769›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2020

Guideline concordant care for prevention of acute chemotherapy-induced nausea and vomiting in children, adolescents, and young adults.

Melissa Beauchemin, Lillian Sung, Dawn L Hershman, Chunhua Weng, L Lee Dupuis, Rebecca Schnall

Open access · greenAbstract read
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

  1. The potential impact of exercise upon symptom burden in adolescents and young adults undergoing cancer treatment.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Trial
  2. Article
  3. Clinical practice guideline- and care pathway-inconsistent care following implementation of adapted infection management care pathways.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  4. Article
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  7. Review
  8. Article
  9. International journal of qualitative studies on health and well-being · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Melissa BeaucheminSchool of Nursing, Columbia University, New York, NY, 10032, USA. mmp2123@cumc.columbia.edu.ORCID https://orcid.org/0000-0003-4058-1586
Lillian SungThe Hospital for Sick Children, Toronto, Canada.
Dawn L HershmanHerbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, 10032, USA.
Chunhua WengDepartment of Biomedical Informatics, Columbia University, New York, NY, 10032, USA.
L Lee DupuisThe Hospital for Sick Children, Toronto, Canada.
Rebecca SchnallSchool of Nursing, Columbia University, New York, NY, 10032, USA.
Columbia University · USColumbia University Irving Medical Center · USHospital for Sick Children · CAUniversity of Toronto · CA

Funding

Reducing Health Disparities Through Informatics - Genomics SupplementT32NR007969 · NINR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SUZANNE BAKKEN, Rebecca Schnall · 2002 to 2026
$7.9M
Reaching Communities through the Design of Information Visualizations (ReDIVis) Toolbox to Address COVID-19 Vaccine Hesitancy and Uptake.P30NR016587 · NINR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BAKKEN, SUZANNE, SMALDONE, ARLENE M · 2016 to 2022
$4.3M
Training Program in Cancer-related Population SciencesT32CA094061 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI NEUGUT, ALFRED I., TERRY, MARY BETH · 2017 to 2021
$1.1M
Mentoring and Research in Self-Management for Health Promotion and Disease PreventionK24NR018621 · NINR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SCHNALL, REBECCA · 2019 to 2022
$384k
NCI NIH HHS T32 CA094061NINR NIH HHS K24 NR018621NINR NIH HHS P30 NR016587NINR NIH HHS T32 NR007969
6 · The paper itself

Abstract

purposePrescribing guideline-recommended anti-emetics is an effective strategy to prevent CINV. However, the rate of guideline-concordant care is not well-understood. The purpose of this study was to describe the proportion of pediatric, adolescent, and young adult patients receiving HEC or MEC who received guideline-concordant antiemetic prophylaxis for acute CINV and to identify potential predictors of guideline-concordant antiemetic prophylaxis.

methodsUsing electronic health record data from 2016 through 2018, a retrospective single-institution cohort study was conducted to investigate how often patients less than 26 years of age receiving moderately or highly emetogenic chemotherapy receive guideline-concordant prophylaxis for acute CINV. Guideline-concordant care was defined according to guidelines from the Pediatric Oncology Group of Ontario for patients < 18 years and the American Society of Clinical Oncology for those ≥ 18 years. Independent variables included: sex, age, insurance status, race, ethnicity, cancer type, chemotherapy regimen, clinical setting, chemotherapy emetogenicity, and patient location. Predictors of receiving guideline-concordant care were determined using multiple logistic regression.

resultsOf 180 eligible patients, 65 (36.1%) received guideline-concordant care. In multivariable analysis, being treated in adult oncology setting (aOR 14.3, CI

conclusionsMulti-level factors were associated with receiving guideline concordant care for prevention of CINV in children, adolescents, and young adults receiving emetogenic chemotherapy. These findings can inform current efforts to optimize implementation strategies for supportive care guidelines.

Indexed as

AdolescentAdultAge FactorsAntiemeticsAntineoplastic AgentsChildCohort StudiesElectronic Health RecordsFemaleGuideline AdherenceHumansInduction ChemotherapyLogistic ModelsMaleMultivariate AnalysisNauseaAntiemeticsAntineoplastic AgentsAYACancerGuideline-concordant careImplementation sciencePediatric

Identifiers

PMID31974769
PMCPMC7375924
OpenAlexW3001627218

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.