Evidence map›Paper›PMID 31974746›Full record

ArticleCardiovascular and interventional radiology2020

Correlation Between Sarcopenia and Growth Rate of the Future Liver Remnant After Portal Vein Embolization in Patients with Colorectal Liver Metastases.

M Schulze-Hagen, D Truhn, F Duong, S Keil, F Pedersoli, C K Kuhl, G Lurje, U Neumann, P Isfort, P Bruners and 1 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cardiovascular and interventional radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

M Schulze-HagenDepartment of Diagnostic and Interventional Radiology, RWTH Aachen University Hospital, Aachen, DE, Germany. mschulze@ukaachen.de.ORCID http://orcid.org/0000-0002-9182-2688
D TruhnInstitute of Imaging and Computer Vision, RWTH Aachen University, Aachen, DE, Germany.
F DuongInstitute of Imaging and Computer Vision, RWTH Aachen University, Aachen, DE, Germany.
S KeilDepartment of Diagnostic and Interventional Radiology, RWTH Aachen University Hospital, Aachen, DE, Germany.
F PedersoliDepartment of Diagnostic and Interventional Radiology, RWTH Aachen University Hospital, Aachen, DE, Germany.
C K KuhlDepartment of Diagnostic and Interventional Radiology, RWTH Aachen University Hospital, Aachen, DE, Germany.
G LurjeDepartment of Surgery and Transplantation, RWTH Aachen University Hospital, Aachen, DE, Germany.
U NeumannDepartment of Surgery and Transplantation, RWTH Aachen University Hospital, Aachen, DE, Germany.
P IsfortDepartment of Diagnostic and Interventional Radiology, RWTH Aachen University Hospital, Aachen, DE, Germany.
P BrunersDepartment of Diagnostic and Interventional Radiology, RWTH Aachen University Hospital, Aachen, DE, Germany.
M ZimmermannDepartment of Diagnostic and Interventional Radiology, RWTH Aachen University Hospital, Aachen, DE, Germany.
Universitätsklinikum Aachen · DERWTH Aachen University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate whether sarcopenia and myosteatosis correlate with the degree of hypertrophy (DH) and kinetic growth rate (KiGR) of the future liver remnant (FLR) in patients with colorectal liver metastases undergoing portal vein embolization (PVE) in preparation for right hepatectomy. MATERIALS AND

methodsForty-two patients were included. Total liver volume and FLR volume were measured before and 2-4 weeks after PVE. KiGR of the FLR was calculated. Sarcopenia was assessed using the total psoas muscle volume (PMV), the psoas muscle cross-sectional area (PMCS) and the total skeletal muscle index (L3SMI) at the level of 3rd lumbar vertebra. Degree of myosteatosis was assessed by mean muscle attenuation at L3 (L3MA). Correlations between muscle indices and DH and KiGR were assessed using simple linear regression analyses.

resultsMean DH was 8.9 ± 5.7%, and mean KiGR was 3.6 ± 2.3. Mean PMV was 55.56 ± 14.19 cm

conclusionWe identified a positive correlation between PMV and PMCS, as markers for sarcopenia, and the KiGR of the FLR after PVE. PMV and PMCS might therefore aid to identify patients who are poor candidates for FLR augmentation using PVE alone.

Indexed as

AdultAgedColorectal NeoplasmsEmbolization, TherapeuticFemaleHumansLiverLiver NeoplasmsMaleMiddle AgedOrgan SizePortal VeinRetrospective StudiesSarcopeniaTomography, X-Ray ComputedUltrasonography, InterventionalFLRLiver hypertrophyPortal vein embolizationPVESarcopenia

Identifiers

PMID31974746
PMCPMC7225189
OpenAlexW3002428922

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.