SynthesisJournal of racial and ethnic health disparities2020
A Systematic Review of Environmental Health Outcomes in Selected American Indian and Alaska Native Populations.
Synthesis in Journal of racial and ethnic health disparities, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 21 citations in OpenAlex.
- Addressing Structural and Systemic Racism in Social and Health Care Systems to Advance Health Equity.Journal of general internal medicine · 2026Article
- Advancing brain health equity with Indigenous peoples: A critical imperative.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Air Pollution Levels in American Indian Communities in the Great Plains and Southwest: The Strong Heart Study.Atmospheric pollution research · 2026Article
- Trusted partners, community priorities, and data protections: requirements for precision medicine research with Alaska Native peoples.Journal of community genetics · 2025Article
- Mixed contaminant exposure in tapwater and the potential implications for human-health in disadvantaged communities in California.Water research · 2024Article
- Incidence of Stomach, Liver, and Colorectal Cancers by Geography and Social Vulnerability Among American Indian and Alaska Native Populations, 2010-2019.American journal of epidemiology · 2024Article
- Medicolegal death investigations on tribal lands-underrepresented or underserved?Forensic science international. Synergy · 2024Article
- Diné Navajo Resilience to the COVID-19 pandemic.PloS one · 2022Article
- Uranium Exposure in American Indian Communities: Health, Policy, and the Way Forward.Environmental health perspectives · 2021Review
- The Ramapough Lunaape Nation: Facing Health Impacts Associated with Proximity to a Superfund Site.Journal of community health · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEconomic and social marginalization among American Indians and Alaska Natives (AI/ANs) results in higher chronic disease prevalence. Potential causal associations between toxic environmental exposures and adverse health outcomes within AI/AN communities are not well understood.
objectivesThis review examines epidemiological literature on exposure to toxicants and associated adverse health outcomes among AI/AN populations.
methodsPubMed, Embase, Cochrane, Environment Complete, Web of Science Plus, DART, and ToxLine were searched for English-language articles. The following data were extracted: lead author's last name, publication year, cohort name, study location, AI/AN tribe, study initiation and conclusion, sample size, primary characteristic, environmental exposure, health outcomes, risk estimates, and covariates.
resultsAbout 31 articles on three types of environmental exposures met inclusion criteria: persistent organic pollutants (POPs), heavy metals, and open dumpsites. Of these, 17 addressed exposure to POPs, 10 heavy metal exposure, 2 exposure to both POPs and heavy metals, and 2 exposure to open dumpsites. Studies on the Mohawk Nation at Akwesasne; Yupik on St. Lawrence Island, Alaska; Navajo Nation; Gila River Indian Community; Cheyenne River Sioux; 197 Alaska Native villages; and 13 tribes in Arizona, Oklahoma, North Dakota, and South Dakota that participated in the Strong Heart Study support associations between toxicant exposure and various chronic conditions including cardiovascular conditions, reproductive abnormalities, cancer, autoimmune disorders, neurological deficits, and diabetes. DISCUSSION: The complex interplay of environmental and social factors in disease etiology among AI/ANs is a product of externally imposed environmental exposures, systemic discrimination, and modifiable risk behaviors. The connection between environmental health disparities and adverse health outcomes indicates a need for further study.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.