Evidence map›Paper›PMID 31974676›Full record

ArticleJournal of bone and mineral metabolism2020

Sub-optimal serum 25-hydroxyvitamin D level affects 2-year survival after hip fracture surgery.

Eric Wei Liang Cher, John Carson Allen, Ing How Moo, Ean Chung Lo, Bryan Peh, Tet Sen Howe, Joyce Suang Bee Koh

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of bone and mineral metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Vitamin D deficiency in hip fracture patients is associated with an increased mortality risk.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024
    Article
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Article
  9. Relatively low and moderate pre-fracture serum 25-hydroxyvitamin D levels associated with the highest survival in elderly hip fracture patients in Finland: a minimum 3-year follow-up.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
    Article
  10. How can the orthopedic surgeon ensure optimal vitamin D status in patients operated for an osteoporotic fracture?Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Eric Wei Liang CherDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore, Singapore. ericcher@gmail.com.ORCID http://orcid.org/0000-0002-4781-965X
John Carson AllenCentre of Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore.
Ing How MooDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore, Singapore.
Ean Chung LoDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore, Singapore.
Bryan PehDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore, Singapore.
Tet Sen HoweDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore, Singapore.
Joyce Suang Bee KohDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHypovitaminosis D is a common condition seen in patients with acute hip fracture. We hypothesize that in addition to the other prognosticating factors, hypovitaminosis D may affect survival in patients treated for hip fractures. The objective of this study is to evaluate the impact of serum level of 25-hydroxyvitamin D (25(OH)D) on the survivability after surgical fixation of hip fractures. MATERIALS AND

methodsWe retrospectively studied data collected from January 2013 through December 2015 at a large tertiary hospital in Singapore. Patient's age, gender, Charlson Comorbidity Index (CCI), delay of surgery, fracture patterns, ASA score, as well as their pre-operative serum levels of 25(OH)D, albumin and calcium were examined. Univariate and multivariate logistic regression were used to analyse post-operative outcomes including short (inpatient, 30 and 90 days) and long-term mortality (2 years).

resultsData from 1004 patients were used. Information on the serum level of 25(OH)D was available in 80% of them (n = 801) and more than 90% (n = 735) of the patients had a baseline serum level of less than 30 ng/ml. Mortality rate within this group were 1.1% (n = 9) at 30 days, 1.9% (n = 15) at 90 days and 11.0% (n = 88) at 2 years follow up. Hypovitaminosis D was not a significant risk predictor for short-term mortality, but found to be a significant predictor at 2 years.

conclusionsIn this study, we showed a high prevalence of hypovitaminosis D among the osteoporotic hip fracture population and its impact on 2-year survivorship after hip fracture surgery.

Indexed as

AgedFemaleFollow-Up StudiesHip FracturesHumansLogistic ModelsMaleMultivariate AnalysisRetrospective StudiesROC CurveSurvival AnalysisVitamin DVitamin D Deficiency25-hydroxyvitamin DVitamin DCharlson comorbidities indexHip fractureHypovitaminosis DMortalityOsteoporotic fracture

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.