Evidence map›Paper›PMID 31974443›Full record

ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2020

Do striatal push/pull circuits hold the key to compulsive, relapsing heroin addiction? : A Research Highlight on: Chemogenetic modulation of accumbens direct or indirect pathways bidirectionally alters reinstatement of heroin-seeking in high- but not low-risk rats, by O'Neal et al. (2019).

Morgan H James, Stephen V Mahler

Abstract readComment
In one paragraph

Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Morgan H JamesBrain Health Institute, Rutgers University, Piscataway, NJ, USA. morgan.james@rutgers.edu.ORCID http://orcid.org/0000-0001-9298-8607
Stephen V MahlerDepartment of Neurobiology & Behavior, University of California Irvine, Irvine, CA, USA.ORCID http://orcid.org/0000-0002-8698-0905

Funding

Impact of Cannabinoid Across the Lifespan (ICAL)P50DA044118 · NIDA · UNIVERSITY OF CALIFORNIA-IRVINE · PI Faizy Ahmed · 2018 to 2026
$18.2M
Orexin/hypocretin as a common mediator of stress and reward behavior in cocaine addictionR00DA045765 · NIDA · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI JAMES, MORGAN H. · 2021 to 2023
$747k
Orexin/hypocretin as a common mediator of stress and reward behavior in cocaine addictionK99DA045765 · NIDA · RBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL · PI JAMES, MORGAN H. · 2019 to 2020
$388k
NIDA NIH HHS K99 DA045765NIDA NIH HHS P50 DA044118NIDA NIH HHS R00 DA045765
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HeroinHeroin DependenceAnimalsCompulsive BehaviorCorpus StriatumNucleus AccumbensRatsHeroin

Identifiers

PMID31974443
PMCPMC7413534

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.