ArticleProceedings of the National Academy of Sciences of the United States of America2020
Wireless, battery-free subdermally implantable photometry systems for chronic recording of neural dynamics.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
58 citing papers in PubMed, 134 citations in OpenAlex.
- Local control of Cre-regulated genetic modeling in vivo using wireless implantable optoelectronics.Science advances · 2026Article
- A Geometrically Transient Platform for Bioelectronic Implants.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Miniscope Zero: a fully wireless, single-cell-resolution miniature microscope for imaging neural dynamics in freely behaving animals.bioRxiv : the preprint server for biology · 2026Article
- Implantable bioelectronic outlet.Science advances · 2026Article
- Robust magnetoelectric backscatter communication system for bioelectronic implants.Communications engineering · 2026Article
- Far-field wireless power transmission module with MEMS-based laser steering for optogenetic applications.iScience · 2025Article
- Neural vs Neuromorphic Interfaces: Where Are We Standing?Chemical reviews · 2025Review
- Analysis and management of thermal loads generated in vivo by miniaturized optoelectronic implantable devices.Device · 2025Article
- An integrated microfluidic and fluorescence platform for probing in vivo neuropharmacology.Neuron · 2025Article
- Continuous operation of battery-free implants enables advanced fracture recovery monitoring.Science advances · 2025Article
- Optogenetic activation of mechanical nociceptions to enhance implant osseointegration.Nature communications · 2025Article
- A soft multimodal optoelectronic array interface for multiparametric mapping of heart function in vivo.Science advances · 2025Article
- Time series segmentation for recognition of epileptiform patterns recorded via microelectrode arrays in vitro.PloS one · 2025Article
- Omnidirectional Wireless Power Transfer for Millimetric Magnetoelectric Biomedical Implants.IEEE journal of solid-state circuits · 2024Article
- Fiber photometry-based investigation of brain function and dysfunction.Neurophotonics · 2024Article
- Review
- Soft ferroelectret ultrasound receiver for targeted peripheral neuromodulation.Nature communications · 2023Article
- Advances in Wireless, Batteryless, Implantable Electronics for Real-Time, Continuous Physiological Monitoring.Nano-micro letters · 2023Review
- Fully implanted battery-free high power platform for chronic spinal and muscular functional electrical stimulation.Nature communications · 2023Article
- Integrated internal ion-gated organic electrochemical transistors for stand-alone conformable bioelectronics.Nature materials · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 3 institutions in 1 country.
Funding
Abstract
Recording cell-specific neuronal activity while monitoring behaviors of freely moving subjects can provide some of the most significant insights into brain function. Current means for monitoring calcium dynamics in genetically targeted populations of neurons rely on delivery of light and recording of fluorescent signals through optical fibers that can reduce subject mobility, induce motion artifacts, and limit experimental paradigms to isolated subjects in open, two-dimensional (2D) spaces. Wireless alternatives eliminate constraints associated with optical fibers, but their use of head stages with batteries adds bulk and weight that can affect behaviors, with limited operational lifetimes. The systems introduced here avoid drawbacks of both types of technologies, by combining highly miniaturized electronics and energy harvesters with injectable photometric modules in a class of fully wireless, battery-free photometer that is fully implantable subdermally to allow for the interrogation of neural dynamics in freely behaving subjects, without limitations set by fiber optic tethers or operational lifetimes constrained by traditional power supplies. The unique capabilities of these systems, their compatibility with magnetic resonant imaging and computed tomography and the ability to manufacture them with techniques in widespread use for consumer electronics, suggest a potential for broad adoption in neuroscience research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.