Evidence map›Paper›PMID 31974297›Full record

ArticleArchives of disease in childhood2020

Evidence of the non-linear nature of skeletal maturation.

Melanie E Boeyer, Emily V Leary, Richard J Sherwood, Dana L Duren

Open access · greenAbstract read
In one paragraph

Article in Archives of disease in childhood, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Estimating Craniofacial Growth Cessation: Comparison of Asymptote- and Rate-Based Methods.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Melanie E BoeyerOrthopaedic Surgery, University of Missouri Columbia, Columbia, Missouri, USA mebk7d@mail.missouri.edu.
Emily V LearyOrthopaedic Surgery, University of Missouri Columbia, Columbia, Missouri, USA.
Richard J SherwoodOrthopaedic Surgery, University of Missouri Columbia, Columbia, Missouri, USA.
Dana L DurenOrthopaedic Surgery, University of Missouri Columbia, Columbia, Missouri, USA.
University of Missouri · US

Funding

SUBCUTANEOUS FAT, BLOOD LIPIDS AND SUBSEQUENT OUTCOMER01HD012252 · NICHD · WRIGHT STATE UNIVERSITY · PI CZERWINSKI, STEFAN A. · 1985 to 2014
$17.3M
Updating Skeletal Maturity Methods for US ChildrenR01AR055927 · NIAMS · WRIGHT STATE UNIVERSITY · PI DUREN, DANA L · 2009 to 2018
$2.4M
Temporal Milestones During Childhood: Identification of a Maturational SpurtF31HD091939 · NICHD · UNIVERSITY OF MISSOURI-COLUMBIA · PI BOEYER, MELANIE EMILY · 2018 to 2020
$113k
NIAMS NIH HHS R01 AR055927NICHD NIH HHS F31 HD091939NICHD NIH HHS R01 HD012252
6 · The paper itself

Abstract

objectiveThe aim of this study was to assess longitudinal trajectories of skeletal maturation to determine if children exhibit periods of rapid maturation during normal childhood and adolescence.

designRetrospective longitudinal study. PATIENTS: 345 participants, with an average of 25 assessments per participant, between 3 and 20 years of age from the Fels Longitudinal Study.

main outcome measure

resultsMore than 81% of participants exhibited a rapid period of skeletal maturation during childhood and/or adolescence, most of whom were characterised by a single maturational spurt during adolescence. Participants with only a single adolescent spurt in skeletal maturation reach adolescent onset and peak approximately 2.8 and 4.2 years earlier, respectively, in boys (p<0.001) and girls (p<0.001), than when compared with participants with both childhood and adolescent spurts. Differences in the timing and tempo of maturational milestones were driven primarily by trajectory type.

conclusionsRapid changes in skeletal maturation occur during normal childhood and/or adolescence, indicating the presence of a maturational spurt: a developmental phenomenon that has remained largely uncharacterised. This work highlights patterned changes in the timing, tempo and duration of longitudinal skeletal maturation while simultaneously shifting the paradigm that skeletal maturation progresses linearly.

Indexed as

Bone DevelopmentAdolescentAdolescent DevelopmentAge FactorsChildChild DevelopmentChild, PreschoolFemaleHumansLongitudinal StudiesMaleNonlinear DynamicsRetrospective StudiesSex FactorsTime FactorsYoung Adultbone ageskeletal ageskeletal maturation

Identifiers

PMID31974297
PMCPMC7592265
OpenAlexW3002741954

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.