Evidence map›Paper›PMID 31973603›Full record

ArticleJournal of the American Heart Association2020

Early Systolic Lengthening in Patients With ST-Segment-Elevation Myocardial Infarction: A Novel Predictor of Cardiovascular Events.

Philip Brainin, Sune Haahr-Pedersen, Flemming Javier Olsen, Anna Engell Holm, Thomas Fritz-Hansen, Thomas Jespersen, Gunnar Gislason, Tor Biering-Sørensen

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Myocardial work in chronic kidney disease: insights from the CPH-CKD ECHO Study.Clinical research in cardiology : official journal of the German Cardiac Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Philip BraininDepartment of Cardiology Herlev and Gentofte Hospital University of Copenhagen Denmark.
Sune Haahr-PedersenDepartment of Cardiology Herlev and Gentofte Hospital University of Copenhagen Denmark.
Flemming Javier OlsenDepartment of Cardiology Herlev and Gentofte Hospital University of Copenhagen Denmark.
Anna Engell HolmDepartment of Cardiology Herlev and Gentofte Hospital University of Copenhagen Denmark.
Thomas Fritz-HansenDepartment of Cardiology Herlev and Gentofte Hospital University of Copenhagen Denmark.
Thomas JespersenDepartment of Biomedical Sciences University of Copenhagen Denmark.
Gunnar GislasonDepartment of Cardiology Herlev and Gentofte Hospital University of Copenhagen Denmark.
Tor Biering-SørensenDepartment of Cardiology Herlev and Gentofte Hospital University of Copenhagen Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Early systolic lengthening (ESL) may occur in ischemic myocardial segments with reduced contractile force. We sought to evaluate the prognostic potential of ESL in patients with ST-segment-elevation myocardial infarction treated with primary percutaneous coronary intervention. Methods and Results We prospectively enrolled 373 patients with ST-segment-elevation myocardial infarction treated with primary percutaneous coronary intervention. All patients underwent a speckle tracking echocardiographic examination a median of 2 days (interquartile range, 1-3 days) after the percutaneous coronary intervention. We assessed a novel viability index, the ESL index, defined as follows: [-100×(peak positive systolic strain/peak negative strain in cardiac cycle)]. We also calculated ESL duration, defined as time from onset of QRS complex on the ECG to time of peak positive systolic strain. Both parameters were averaged from 18 myocardial segments. During a median follow-up of 5.3 years (interquartile range, 2.5-6.0 years), 145 (39%) experienced major adverse cardiovascular events, a composite of incident heart failure, new myocardial infarction, and all-cause mortality. The ESL index and ESL duration were significantly increased in culprit lesion areas (6.7±6.2% versus 5.0±4.1% and 43±33 ms versus 33±24 ms, respectively;

Indexed as

Echocardiography, Doppler, ColorEchocardiography, Doppler, PulsedPercutaneous Coronary InterventionVentricular Function, LeftAgedFemaleHeart Disease Risk FactorsHeart FailureHumansMaleMiddle AgedPredictive Value of TestsProspective StudiesRisk AssessmentST Elevation Myocardial InfarctionSystole2‐dimensional speckle tracking echocardiographydeformationearly systolic lengtheningechocardiographymyocardial infarctionrevascularization

Identifiers

PMID31973603
PMCPMC7033900

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.