Evidence map›Paper›PMID 31973216›Full record

ArticleGenes2020

Eag1 Gene and Protein Expression in Human Retinoblastoma Tumors and its Regulation by pRb in HeLa Cells.

María de Guadalupe Chávez-López, Violeta Zúñiga-García, Blanca Elena Castro-Magdonel, Eunice Vera, Efraín Garrido, Janet Sánchez-Ramos, M Verónica Ponce-Castañeda, M de Lourdes Cabrera-Muñoz, Yesenia Escobar, Cindy Sharon Ortiz and 3 more

Open access · goldAbstract read
In one paragraph

Article in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. The mechanism study ofTranslational cancer research · 2022
    Article
  4. The hEag1 KInternational journal of molecular sciences · 2022
    Article
  5. Article
  6. Review
  7. Review
  8. EngineeringAIChE journal. American Institute of Chemical Engineers · 2021
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

María de Guadalupe Chávez-LópezDepartment of Pharmacology, Centro de Investigación y de Estudios Avanzados del I.P.N., Mexico City 07360, Mexico.
Violeta Zúñiga-GarcíaDepartment of Pharmacology, Centro de Investigación y de Estudios Avanzados del I.P.N., Mexico City 07360, Mexico.
Blanca Elena Castro-MagdonelDepartment of Pharmacology, Centro de Investigación y de Estudios Avanzados del I.P.N., Mexico City 07360, Mexico.
Eunice VeraDepartment of Pharmacology, Centro de Investigación y de Estudios Avanzados del I.P.N., Mexico City 07360, Mexico.
Efraín GarridoDepartment of Genetics and Molecular Biology, Centro de Investigación y de Estudios Avanzados del I.P.N., Mexico City 07360, Mexico.
Janet Sánchez-RamosDepartment of Genetics and Molecular Biology, Centro de Investigación y de Estudios Avanzados del I.P.N., Mexico City 07360, Mexico.
M Verónica Ponce-CastañedaHospital de Pediatría, Unidad de Investigación Médica en Enfermedades Infecciosas, CMN SXXI, IMSS, Mexico City 06720, Mexico.
M de Lourdes Cabrera-MuñozDepartment of Pathology, Hospital Infantil de México Federico Gómez, Secretaría de Salud, Mexico City 06720, Mexico.
Yesenia EscobarCentro de Investigación Clínica Acelerada SC, Mexico City 07020, Mexico.
Cindy Sharon OrtizDepartamento de Radioterapia. Hospital Regional de Alta Especialidad del Bajío. León, Gto. 37660, Mexico.
Elisabeth Hernández-GallegosDepartment of Pharmacology, Centro de Investigación y de Estudios Avanzados del I.P.N., Mexico City 07360, Mexico.
Arturo Avalos-FuentesDepartment of Physiology, Biophysics and Neuroscience, Centro de Investigación y de Estudios Avanzados del I.P.N., Mexico City 07360, Mexico.
Javier CamachoDepartment of Pharmacology, Centro de Investigación y de Estudios Avanzados del I.P.N., Mexico City 07360, Mexico.
Centro de Investigación en Materiales Avanzados · MXHospital Regional de Alta Especialidad del Bajío · MXMexican Social Security Institute · MXSecretaria de Salud · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retinoblastoma is the most common pediatric intraocular malignant tumor. Unfortunately, low cure rates and low life expectancy are observed in low-income countries. Thus, alternative therapies are needed for patients who do not respond to current treatments or those with advanced cases of the disease.

Indexed as

AstemizoleCell Line, TumorCell ProliferationChild, PreschoolEther-A-Go-Go Potassium ChannelsFemaleGene Expression Regulation, NeoplasticHeLa CellsHumansInfantMaleOncogenesRetinal NeoplasmsRetinoblastomaRetinoblastoma ProteinRNA, MessengerAstemizoleEther-A-Go-Go Potassium ChannelsKCNH1 protein, humanRetinoblastoma ProteinRNA, MessengerastemizoleEag1 channelsKCNH1Kv10.1potassium channelsretinoblastomatumor suppressor

Identifiers

PMID31973216
PMCPMC7074590
OpenAlexW3000962322

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.