Evidence map›Paper›PMID 31972983›Full record

ArticleInternational journal of molecular sciences2020

The Probiotic BB12 Induces MicroRNAs Involved in Antigen Processing and Presentation in Porcine Monocyte-Derived Dendritic Cells.

Marlene Bravo-Parra, Marina Arenas-Padilla, Valeria Brcenas-Preciado, Jesús Hernández, Verónica Mata-Haro

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Marlene Bravo-ParraLaboratory of Microbiology and Immunology, Ciencia de los Alimentos, Centro de Investigación en Alimentación y Desarrollo A. C. (CIAD). Carretera Gustavo Astiazarán Rosas 46, Col. la Victoria, Hermosillo 83304, Sonora, Mexico.
Marina Arenas-PadillaLaboratory of Microbiology and Immunology, Ciencia de los Alimentos, Centro de Investigación en Alimentación y Desarrollo A. C. (CIAD). Carretera Gustavo Astiazarán Rosas 46, Col. la Victoria, Hermosillo 83304, Sonora, Mexico.
Valeria Brcenas-PreciadoLaboratory of Microbiology and Immunology, Ciencia de los Alimentos, Centro de Investigación en Alimentación y Desarrollo A. C. (CIAD). Carretera Gustavo Astiazarán Rosas 46, Col. la Victoria, Hermosillo 83304, Sonora, Mexico.
Jesús HernándezLaboratory of Immunology, Centro de Investigación en Alimentación y Desarrollo A. C. (CIAD), México, Carretera Gustavo Astiazarán Rosas 46, Col. la Victoria, Hermosillo 83304, Sonora, Mexico.
Verónica Mata-HaroLaboratory of Microbiology and Immunology, Ciencia de los Alimentos, Centro de Investigación en Alimentación y Desarrollo A. C. (CIAD). Carretera Gustavo Astiazarán Rosas 46, Col. la Victoria, Hermosillo 83304, Sonora, Mexico.
Centro de Investigación en Alimentación y Desarrollo · MX

Funding

Consejo Nacional de Ciencia y Tecnología 257462
6 · The paper itself

Abstract

MicroRNAs (miRNAs) mediate the regulation of gene expression. Several reports indicate that probiotics induce miRNA-mediated immunomodulation at different levels, such as cytokine production and the up-regulation of several markers related to antigen presentation in antigen-presenting cells. The objective of this work was to identify target genes of miRNAs that are involved in the processing and presentation of antigens in monocyte-derived dendritic cells (moDCs) stimulated with the probiotic

Indexed as

AnimalsAntigen PresentationB7-1 AntigenBifidobacterium animalisCytokinesDendritic CellsDown-RegulationGene Expression ProfilingImmunomodulationInterleukin-10MicroRNAsMonocytesProbioticsRNA, MessengerSwineUp-RegulationB7-1 AntigenCytokinesInterleukin-10MicroRNAsRNA, Messengercostimulatory moleculesIL-10MHC II pathwaymicroarraymicroRNAsporcine moDCsprobiotics

Identifiers

PMID31972983
PMCPMC7037397
OpenAlexW3002537864

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.