Evidence map›Paper›PMID 31972961›Full record

ArticleAnimals : an open access journal from MDPI2020

Objective Comparison between Platelet Rich Plasma Alone and in Combination with Physical Therapy in Dogs with Osteoarthritis Caused by Hip Dysplasia.

Belén Cuervo, Mónica Rubio, Deborah Chicharro, Elena Damiá, Angelo Santana, José María Carrillo, Ayla Del Romero, José Manuel Vilar, José Joaquín Cerón, Joaquín Jesús Sopena

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 34 citations in OpenAlex.

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  7. Chronic osteoarthritis caused byJournal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Belén CuervoBioregenerative Medicine and Applied Surgery Research Group, Departamento de medicina y cirugía animal, Facultad de veterinaria, Universidad Cardenal Herrera-CEU, CEU Universities, 46115 Valencia, Spain.ORCID 0000-0002-8104-4560
Mónica RubioBioregenerative Medicine and Applied Surgery Research Group, Departamento de medicina y cirugía animal, Facultad de veterinaria, Universidad Cardenal Herrera-CEU, CEU Universities, 46115 Valencia, Spain.ORCID 0000-0002-2689-8862
Deborah ChicharroBioregenerative Medicine and Applied Surgery Research Group, Departamento de medicina y cirugía animal, Facultad de veterinaria, Universidad Cardenal Herrera-CEU, CEU Universities, 46115 Valencia, Spain.ORCID 0000-0002-1121-1327
Elena DamiáBioregenerative Medicine and Applied Surgery Research Group, Departamento de medicina y cirugía animal, Facultad de veterinaria, Universidad Cardenal Herrera-CEU, CEU Universities, 46115 Valencia, Spain.
Angelo SantanaDepartment of Mathematics, Universidad de Las Palmas de Gran Canaria, Campus de Tafira, 35018 Las Palmas, Spain.ORCID 0000-0002-6513-4814
José María CarrilloBioregenerative Medicine and Applied Surgery Research Group, Departamento de medicina y cirugía animal, Facultad de veterinaria, Universidad Cardenal Herrera-CEU, CEU Universities, 46115 Valencia, Spain.
Ayla Del RomeroBioregenerative Medicine and Applied Surgery Research Group, Departamento de medicina y cirugía animal, Facultad de veterinaria, Universidad Cardenal Herrera-CEU, CEU Universities, 46115 Valencia, Spain.
José Manuel VilarDepartment of Animal Pathology, Instituto Universitario de Investigaciones Biomédicas y Universitarias, Universidad de Las Palmas de Gran Canaria, 35416 Trasmontaña S/N. Arucas, Spain.ORCID 0000-0002-2060-2274
José Joaquín CerónGarcía Cugat Foundation CEU-UCH Chair of Medicine and Regenerative Surgery, 08006 Barcelona, Spain.
Joaquín Jesús SopenaBioregenerative Medicine and Applied Surgery Research Group, Departamento de medicina y cirugía animal, Facultad de veterinaria, Universidad Cardenal Herrera-CEU, CEU Universities, 46115 Valencia, Spain.ORCID 0000-0002-3601-9745
Universidad Cardenal Herrera CEU · ESUniversidad de Las Palmas de Gran Canaria · ESUniversidad de Murcia · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoarthritis (OA) is one of the most significant joint diseases worldwide. There are different therapies for OA treatment, and a relatively new strategy is the use of plasma rich in growth factors (PRGF), a platelet rich plasma (PRP) derivative. The objective of this study was to objectively assess the efficacy and duration of the effect of an intraarticular injection of PRGF and a combination of PRGF + physical therapy. The objective assessment was provided using a force platform. The obtained parameters were peak vertical force (PVF) and vertical impulse (VI). A total of 24 dogs with lameness and pain associated to OA attributable to bilateral hip dysplasia were included in the study. Animals were divided into two study groups and evaluated at baseline and at 30, 90, and 180 days after intraarticular PRGF or PRGF + physical therapy. Significant differences were observed at every checkpoint with respect to basal time in both groups. However, after 180 days, the PRGF group showed a decrease in PVF and VI with respect to the values obtained at 90 days. However, the PRGF + physical therapy group maintained increased values of both PVF and VI values during the 180-day study period.

Indexed as

biomarkerscanineosteoarthritisphysical therapyplasma rich in growth factorsplatelet rich plasma

Identifiers

PMID31972961
PMCPMC7070503
OpenAlexW2999687009

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.