Evidence map›Paper›PMID 31972760›Full record

ArticleJournal of addiction medicine

Association Between Recent Cannabis Consumption and Withdrawal-Related Symptoms During Early Abstinence Among Females With Smoked Cocaine Use Disorder.

Thiago Wendt Viola, Breno Sanvicente-Vieira, Bruno Kluwe-Schiavon, Leonardo Melo Rothmann, João Vítor Nóbrega E Mélo-Pereira, Carla Bicca, João Paulo Ottolia Niederauer, Joy Schmitz, Rodrigo Grassi-Oliveira

Open access · greenAbstract read
In one paragraph

Article in Journal of addiction medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Thiago Wendt ViolaPontifical Catholic University of Rio Grande do Sul (PUCRS), Developmental Cognitive Neuroscience Lab, Porto Alegre, RS, Brazil (TWV, LMR, JVNMP, CB, JPN, RG-O); Experimental and Clinical Pharmacopsychology Laboratory, Department of Psychiatry, Psychotherapy, and Psychosomatics, Psychiatric Hospital, University of Zurich, Switzerland (BK-S); Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston, TX (JS); Pontifical Catholic University of Rio de Janeiro (PUC-Rio), Department of Psychology, Rio de Janeiro, RJ, Brazil (BS-V).
Breno Sanvicente-Vieira
Bruno Kluwe-Schiavon
Leonardo Melo Rothmann
João Vítor Nóbrega E Mélo-Pereira
Carla Bicca
João Paulo Ottolia Niederauer
Joy Schmitz
Rodrigo Grassi-Oliveira
Baria Vungtau University · VN

Funding

Gene-environment interactions in COCCaINE Use Disorder: Collaborative Case-Control Initiative in Coccaine AddictionR01DA044859 · NIDA · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI GRASSI-OLIVEIRA, RODRIGO, SCHMITZ, JOY MARIE · 2017 to 2021
$2.8M
NIDA NIH HHS R01 DA044859
6 · The paper itself

Abstract

backgroundThe effects of cannabis on clinical outcomes of treatment services for other drug use disorders remains unclear. The primary aim of the current study was to investigate the effects of recent cannabis consumption on the severity of cocaine withdrawal and depressive symptoms during a 3-week inpatient treatment program for women with cocaine use disorder. The second goal of this study was to test the effect of recent alcohol or tobacco use on the aforementioned outcomes.

methodsThis was a longitudinal study with 2 assessment time points: at enrollment and upon discharge from a medically managed intensive inpatient unit. The sample was composed of 214 early abstinence females with cocaine use disorder. Cocaine withdrawal and depressive symptoms were measured using the Cocaine Selective Severity Assessment (CSSA) and the Beck Depressive Inventory (BDI-II). Recent substance use was evaluated using the Addiction Severity Index (ASI-6).

resultsPatients with cocaine use disorder and with frequent recent cannabis use reported higher severity of cocaine withdrawal and depressive symptoms after 3 weeks of inpatient treatment. Neither recent alcohol nor tobacco use was associated with increased CSSA or BDI outcomes, suggesting these substances play a minor role compared to recent cannabis use in affecting withdrawal-related symptoms.

conclusionsThe assessment of recent cannabis use may help identify patients in need of additional treatment to manage severe cocaine withdrawal symptoms and depressive symptoms during early abstinence.

Indexed as

CannabisCocaineCocaine-Related DisordersSubstance-Related DisordersSubstance Withdrawal SyndromeFemaleHumansLongitudinal StudiesSmokeCocaineSmoke

Identifiers

PMID31972760
PMCPMC7358113
OpenAlexW3000210650

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.