Evidence map›Paper›PMID 31972203›Full record

ReviewNeuroscience and biobehavioral reviews2020

Mapping sign-tracking and goal-tracking onto human behaviors.

Janna M Colaizzi, Shelly B Flagel, Michelle A Joyner, Ashley N Gearhardt, Jennifer L Stewart, Martin P Paulus

Registry-linked trialAbstract readReview
In one paragraph

Review in Neuroscience and biobehavioral reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05456516 (Neurocognitive and Behavioral Factors That Promote Resiliency to Pediatric Obesity), which is not on this map. Cited by 57 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05456516 nacompletednot on this mapstarted 2023, after this paper: background citation

Neurocognitive and Behavioral Factors That Promote Resiliency to Pediatric Obesity

TypeinterventionalSponsorPenn State UniversityRan2023 to 2024Enrolled76ConditionsObesity, Childhood, Eating BehaviorArmsFood Rating
3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Prediction and Prioritisation: How Reward Learning Shapes Attentional Capture.Quarterly journal of experimental psychology (2006) · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Addiction biology · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Reduced Pavlovian Value Updating Alters Decision-Making in Sign-Trackers.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Janna M ColaizziLaureate Institute for Brain Research, 6655 S Yale Ave, Tulsa, OK, USA. Electronic address: jcolaizzi@laureateinstitute.org.
Shelly B FlagelUniversity of Michigan Molecular and Behavioral Neuroscience Institute, 205 Zina Pitcher Pl, Ann Arbor, MI, 48109, USA.
Michelle A JoynerUniversity of Michigan, Department of Psychology, 530 Church St, Ann Arbor, MI, 48109, USA.
Ashley N GearhardtUniversity of Michigan, Department of Psychology, 530 Church St, Ann Arbor, MI, 48109, USA.
Jennifer L StewartLaureate Institute for Brain Research, 6655 S Yale Ave, Tulsa, OK, USA.
Martin P PaulusLaureate Institute for Brain Research, 6655 S Yale Ave, Tulsa, OK, USA.

Funding

The Center for Neuroscience-based Mental Health Assessment and Prediction (NEUROMAP)P20GM121312 · NIGMS · LAUREATE INSTITUTE FOR BRAIN RESEARCH · PI Maëlle Camille Marie Gueguen · 2017 to 2026
$23.7M
NIGMS NIH HHS P20 GM121312
6 · The paper itself

Abstract

As evidenced through classic Pavlovian learning mechanisms, environmental cues can become incentivized and influence behavior. These stimulus-outcome associations are relevant in everyday life but may be particularly important for the development of impulse control disorders including addiction. Rodent studies have elucidated specific learning profiles termed 'sign-tracking' and 'goal-tracking' which map onto individual differences in impulsivity and other behaviors associated with impulse control disorders' etiology, course, and relapse. Whereas goal-trackers are biased toward the outcome, sign-trackers fixate on features that are associated with but not necessary for achieving an outcome; a pattern of behavior that often leads to escalation of reward-seeking that can be maladaptive. The vast majority of the sign- and goal-tracking research has been conducted using rodent models and very few have bridged this concept into the domain of human behavior. In this review, we discuss the attributes of sign- and goal-tracking profiles, how these are manifested neurobiologically, and how these distinct learning styles could be an important tool for clinical interventions in human addiction.

Indexed as

CuesGoalsRewardAnimalsBehavior, AddictiveBehavior, AnimalBrainConditioning, ClassicalDisruptive, Impulse Control, and Conduct DisordersExecutive FunctionHumansNerve NetPsychomotor PerformanceAddictive behaviorGoal-trackingHumansImpulse control disordersRodentsSign-tracking

Identifiers

PMID31972203
PMCPMC8087151

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.