Evidence map›Paper›PMID 31972142›Full record

ArticleNeuron2020

Greasing the Wheels of Regeneration.

Rafi Kohen, Roman J Giger

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Neuron, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Ocular Treatments Targeting Separate Prostaglandin Receptors in Mice Exhibit Alterations in Intraocular Pressure and Optic Nerve Lipidome.Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Rafi KohenNeuroscience Graduate Program, University of Michigan Medical School, 2045 BSRB, 109 Zina Pitcher Place, Ann Arbor, MI 48109-2200, USA.
Roman J GigerNeuroscience Graduate Program, University of Michigan Medical School, 2045 BSRB, 109 Zina Pitcher Place, Ann Arbor, MI 48109-2200, USA; Department of Cell & Developmental Biology, University of Michigan Medical School, 2045 BSRB, 109 Zina Pitcher Place, Ann Arbor, MI 48109-2200, USA; Department of Neurology, University of Michigan Medical School, 2045 BSRB, 109 Zina Pitcher Place, Ann Arbor, MI 48109-2200, USA. Electronic address: rgiger@umich.edu.
University of Michigan · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this issue of Neuron, Yang et al. (2020) identify glycerolipid metabolism as a neuron-intrinsic mechanism that regulates axonal growth and regeneration. Shifting glycerolipid metabolism toward increased triglyceride synthesis blocks PNS neuron regeneration, whereas shifting it toward membrane phospholipid synthesis overcomes regeneration failure in CNS neurons.

Indexed as

AxonsNerve RegenerationNeurons

Identifiers

PMID31972142
OpenAlexW3001071093

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.