ReviewAngewandte Chemie (International ed. in English)2020
Parahydrogen-Induced Hyperpolarization of Gases.
Review in Angewandte Chemie (International ed. in English), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed.
- Parahydrogen-Hyperpolarized Propane-The journal of physical chemistry. A · 2025Article
- Toward Lung Ventilation Imaging Using Hyperpolarized Diethyl Ether Gas Contrast Agent.Chemistry (Weinheim an der Bergstrasse, Germany) · 2024Article
- Ultra-Low-Cost Disposable Hand-Held Clinical-Scale Propane Gas Hyperpolarizer for Pulmonary Magnetic Resonance Imaging Sensing.ACS sensors · 2023Article
- Real-Time Reaction Monitoring of Azide-Alkyne Cycloadditions Using Benchtop NMR-Based Signal Amplification by Reversible Exchange (SABRE).ACS measurement science au · 2023Article
- Reconversion of Parahydrogen Gas in Surfactant-Coated Glass NMR Tubes.Molecules (Basel, Switzerland) · 2023Article
- Recent advances in the application of parahydrogen in catalysis and biochemistry.RSC advances · 2022Review
- Pilot Quality-Assurance Study of a Third-Generation Batch-Mode Clinical-Scale Automated Xenon-129 Hyperpolarizer.Molecules (Basel, Switzerland) · 2022Article
- Instrumentation for Hydrogenative Parahydrogen-Based Hyperpolarization Techniques.Analytical chemistry · 2022Article
- Low-Cost High-Pressure Clinical-Scale 50% Parahydrogen Generator Using Liquid Nitrogen at 77 K.Analytical chemistry · 2021Article
- Low-Flammable Parahydrogen-Polarized MRI Contrast Agents.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021Article
- Article
- Heterogeneous Parahydrogen-Induced Polarization of Diethyl Ether for Magnetic Resonance Imaging Applications.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021Article
- Pd-based bimetallic catalysts for parahydrogen-induced polarization in heterogeneous hydrogenations.Magnetic resonance (Gottingen, Germany) · 2021Article
- Chemical Reaction Monitoring using Zero-Field Nuclear Magnetic Resonance Enables Study of Heterogeneous Samples in Metal Containers.Angewandte Chemie (International ed. in English) · 2020Article
- Recent Advances in Chemical Biology Using Benzophenones and Diazirines as Radical Precursors.Molecules (Basel, Switzerland) · 2020Review
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Imaging of gases is a major challenge for any modality including MRI. NMR and MRI signals are directly proportional to the nuclear spin density and the degree of alignment of nuclear spins with applied static magnetic field, which is called nuclear spin polarization. The level of nuclear spin polarization is typically very low, i.e., one hundred thousandth of the potential maximum at 1.5 T and a physiologically relevant temperature. As a result, MRI typically focusses on imaging highly concentrated tissue water. Hyperpolarization methods transiently increase nuclear spin polarizations up to unity, yielding corresponding gains in MRI signal level of several orders of magnitude that enable the 3D imaging of dilute biomolecules including gases. Parahydrogen-induced polarization is a fast, highly scalable, and low-cost hyperpolarization technique. The focus of this Minireview is to highlight selected advances in the field of parahydrogen-induced polarization for the production of hyperpolarized compounds, which can be potentially employed as inhalable contrast agents.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.