Evidence map›Paper›PMID 31971973›Full record

ArticlePloS one2020

Co-prevalence of extracranial carotid aneurysms differs between European intracranial aneurysm cohorts.

Constance J H C M van Laarhoven, Vanessa E C Pourier, Antti E Lindgren, Mervyn D I Vergouwen, Juha E Jääskeläinen, Gabriël J E Rinkel, Dominique P V de Kleijn, Gert J de Borst

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Carotid tortuosity is associated with extracranial carotid artery aneurysms.Quantitative imaging in medicine and surgery · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Constance J H C M van LaarhovenDepartment of Vascular Surgery, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.ORCID 0000-0002-8817-7315
Vanessa E C PourierDepartment of Vascular Surgery, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.
Antti E LindgrenDepartment of Neurosurgery, NeuroCenter, Kuopio University Hospital, Kuopio, Finland.
Mervyn D I VergouwenBrain Center Rudolf Magnus, Department of Neurology and Neurosurgery, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.
Juha E JääskeläinenDepartment of Neurosurgery, NeuroCenter, Kuopio University Hospital, Kuopio, Finland.
Gabriël J E RinkelBrain Center Rudolf Magnus, Department of Neurology and Neurosurgery, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.
Dominique P V de KleijnDepartment of Vascular Surgery, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.
Gert J de BorstDepartment of Vascular Surgery, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.
Utrecht University · NLKuopio University Hospital · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposePreviously, we showed that co-prevalence of extracranial carotid artery aneurysms (ECAAs) in patients with intracranial aneurysms (IAs) was 2% in a Dutch cohort. In order to obtain more precise estimates and discover potential predictors of ECAA co-prevalence in the European population, we retrospectively compared differences and similarities of our Dutch cohort with a Finnish cohort using protocolled imaging of the cerebrovascular tree.

methodsIA patients within the prospective database of the Kuopio University Hospital were eligible for this study (n = 1,118). Image analysis and hospital chart review were conducted.

resultsIn total, 458 patients with complete carotid imaging conform protocol were analyzed. Twenty-four ECAAs in 21 patients were identified (4.6%, 95% CI 2.9-6.9), a higher co-prevalence than in the Dutch cohort (1.9%; 95% CI 1.0-3.3), prevalence odds ratio (POR) 2.45 (95% CI 1.19-5.03). In the Finnish cohort, 25% of all ECAAs were located around the carotid bifurcation, others in the internal carotid artery distally from the bifurcation. Independent predictors for ECAA co-prevalence were origin of country (POR 2.41, 95% CI 1.15-5.06) and male gender (POR 2.25, 95% CI 1.09-4.64).

conclusionThe co-prevalence of ECAA in IA patients was twice as high in the Finnish compared to the Dutch IA cohort, with origin of country and male gender as independent predictors. Twenty-five percent of ECAAs would be missed, if the carotid bifurcation was not imaged. Therefore, we propose to always include imaging of the carotid bifurcation as the gold standard technique to identify ECAA in IA patients.

Indexed as

Angiography, Digital SubtractionCarotid ArteriesCohort StudiesEuropeFemaleHumansIntracranial AneurysmLogistic ModelsMaleMiddle AgedPrevalence

Identifiers

PMID31971973
PMCPMC6977743
OpenAlexW3002563184

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.