Evidence map›Paper›PMID 31971634›Full record

ArticleMagnetic resonance in medicine2020

Improving PCASL at ultra-high field using a VERSE-guided parallel transmission strategy.

Yan Tong, Peter Jezzard, Thomas W Okell, William T Clarke

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
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  5. Article
  6. Dynamic BMagnetic resonance in medicine · 2025
    Article
  7. Head-and-neck multichannel B1Magnetic resonance in medicine · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Neuroimaging at 7 Tesla: a pictorial narrative review.Quantitative imaging in medicine and surgery · 2022
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yan TongWellcome Centre for Integrative Neuroimaging, FMRIB Division, Nuffield Department of Clinical Neurosciences, University of Oxford, United Kingdom.ORCID 0000-0003-2158-2866
Peter JezzardWellcome Centre for Integrative Neuroimaging, FMRIB Division, Nuffield Department of Clinical Neurosciences, University of Oxford, United Kingdom.ORCID 0000-0001-7912-2251
Thomas W OkellWellcome Centre for Integrative Neuroimaging, FMRIB Division, Nuffield Department of Clinical Neurosciences, University of Oxford, United Kingdom.ORCID 0000-0001-8258-0659
William T ClarkeWellcome Centre for Integrative Neuroimaging, FMRIB Division, Nuffield Department of Clinical Neurosciences, University of Oxford, United Kingdom.ORCID 0000-0001-7159-7025

Funding

Department of HealthMedical Research Council MR/N008537/1Wellcome TrustWellcome Trust 203139/Z/16/Z
6 · The paper itself

Abstract

purposeTo improve the labeling efficiency of pseudo-continuous arterial spin labeling (PCASL) at 7T using parallel transmission (pTx).

methodsFive healthy subjects were scanned on an 8-channel-transmit 7T human MRI scanner. Time-of-flight (TOF) angiography was acquired to identify regions of interest (ROIs) around the 4 major feeding arteries to the brain, and

resultsIn simulation, VERSE with RF shimming improved the flip-angles across the ROIs in the labeling plane by 90% compared with CP mode. VERSE with RF shimming improved the temporal signal-to-noise ratio by 375% compared with CP mode, but did not outperform a matched 3T sequence with a matched flip-angle.

conclusionWe have demonstrated improved PCASL tagging at 7T using VERSE with RF shimming on a commercial head coil under conservative SAR limits at 7T. However, improvements of 7T over 3T may require strategies with less conservative SAR restrictions.

Indexed as

AlgorithmsImage Processing, Computer-AssistedArteriesBrainHumansMagnetic Resonance ImagingSpin LabelsSpin Labelsparallel transmission (pTx)perfusionpseudo-continuous arterial spin labelingRF shimmingultra-high field

Identifiers

PMID31971634
PMCPMC7216913

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.