Evidence map›Paper›PMID 31971301›Full record

ArticleNMR in biomedicine2020

Simultaneous multislice rapid magnetic resonance elastography of the liver.

Waqas Majeed, Prateek Kalra, Arunark Kolipaka

Open access · hybridAbstract read
In one paragraph

Article in NMR in biomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Waqas MajeedDepartment of Radiology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.ORCID 0000-0002-1280-0238
Prateek KalraDepartment of Radiology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Arunark KolipakaDepartment of Radiology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
The Ohio State University Wexner Medical Center · US

Funding

Magnetic Resonance ElastographyR37EB001981 · NIBIB · MAYO CLINIC ROCHESTER · PI EHMAN, RICHARD L. · 2016 to 2025
$4.0M
Magnetic Resonance ElastographyR01EB001981 · NIBIB · MAYO CLINIC ROCHESTER · PI EHMAN, RICHARD L. · 2003 to 2013
$3.1M
Improved Understanding of Abdominal Aortic Aneurysm Progression using MR ElastographyR01HL124096 · NHLBI · OHIO STATE UNIVERSITY · PI KOLIPAKA, ARUNARK · 2015 to 2019
$2.4M
NHLBI NIH HHS R01 HL124096NIBIB NIH HHS R01 EB001981NIBIB NIH HHS R37 EB001981
6 · The paper itself

Abstract

To design and validate a rapid Simultaneous Multi-slice (SMS) Magnetic Resonance Elastography technique (MRE), which combines SMS acquisition, in-plane undersampling and an existing rapid Magnetic Resonance Elastography (MREr) scheme to allow accelerated data acquisition in healthy volunteers and comparison against MREr. SMS-MREr sequence was developed by incorporating SMS acquisition scheme into an existing MREr sequence that accelerates MRE acquisition by acquiring data during opposite phases of mechanical vibrations. The MREr sequence accelerated MRE acquisition by acquiring data during opposite phases of mechanical vibrations. Liver MRE was performed on 23 healthy subjects using MREr and SMS-MREr sequences, and mean stiffness values were obtained for manually drawn regions of interest. Linear correlation and agreement between MREr- and SMS-MREr-based stiffness values were investigated. SMS-MREr reduced the scan time by half relative to MREr, and allowed acquisition of four-slice MRE data in a single 17-second breath-hold. Visual comparison suggested agreement between MREr and SMS-MREr elastograms. A Pearson's correlation of 0.93 was observed between stiffness values derived from MREr and SMS-MREr. Bland-Altman analysis demonstrated good agreement, with -0.08 kPa mean bias and narrow limits of agreement (95% CI: 0.23 to -0.39 kPa) between stiffness values obtained using MREr and SMS-MREr. SMS can be combined with other fast MRE approaches to achieve further acceleration. This pushes the limit on the acceleration that can be achieved in MRE acquisition, and makes it possible to conduct liver MRE exams in a single breath-hold.

Indexed as

Elasticity Imaging TechniquesMagnetic Resonance ImagingAdultAgedBiomechanical PhenomenaFemaleHumansLiverMaleMiddle AgedPhantoms, ImagingReproducibility of ResultsSignal-To-Noise RatioYoung Adulthepatobiliarymagnetic resonance elastographyparallel imagingSMSSMS-MRE

Identifiers

PMID31971301
PMCPMC7286422
OpenAlexW3002853207

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.