SynthesisThe neuroradiology journal2020
Radiological predictors of hemorrhagic transformation after acute ischemic stroke: An evidence-based analysis.
Synthesis in The neuroradiology journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Machine learning and deep learning algorithms in stroke medicine: a systematic review of hemorrhagic transformation prediction models.Journal of neurology · 2024Pooled it
- Association between CT Perfusion Parameters and Hemorrhagic Transformation after Endovascular Treatment in Acute Ischemic Stroke: Results from the ESCAPE-NA1 Trial.AJNR. American journal of neuroradiology · 2024Trial
- Blood Flow Restriction Training in Stroke Rehabilitation: A Narrative Review of Current Evidence and Future Directions.Brain and behavior · 2026Review
- Sterile Vegetations in Malignancy: A Rare Case of Nonbacterial Thrombotic Endocarditis in a Patient with Metastatic Melanoma.Reports (MDPI) · 2026Article
- Volumetric Infarct Size Predicts Secondary Haemorrhagic Transformation of Ischaemic Stroke.Cerebrovascular diseases (Basel, Switzerland) · 2026Article
- Fusion Learning from Non-contrast CT Scans for the Detection of Hemorrhagic Transformation in Stroke Patients.Journal of imaging informatics in medicine · 2025Article
- Hypoperfusion Intensity Ratio Less Than 0.4 Is Associated with Favorable Outcomes in Unsuccessfully Reperfused Acute Ischemic Stroke with Large-Vessel Occlusion.AJNR. American journal of neuroradiology · 2025Article
- Assessment of cerebral hemodynamic changes in acute ischemic stroke patients following mechanical thrombectomy using CT perfusion imaging.Frontiers in neurology · 2025Article
- Update of Anticoagulation Use in Cardioembolic Stroke With a Special Reference to Endovascular Treatment.Journal of stroke · 2024Review
- Computed Tomography Perfusion Parameters Predictive of Symptomatic Intracranial Hemorrhage After Mechanical Thrombectomy in Patients With Cerebral Large Vessel Occlusion.Stroke (Hoboken, N.J.) · 2023Article
- Proposal of multimodal computed tomography-based scoring system in prediction of hemorrhagic transformation in acute ischemic stroke.Acta neurologica Belgica · 2023Article
- The role of automated computed topography perfusion in prediction of hemorrhagic transformation after acute ischemic stroke.The neuroradiology journal · 2023Article
- A deep learning-based model for prediction of hemorrhagic transformation after stroke.Brain pathology (Zurich, Switzerland) · 2023Article
- Qixue Shuangbu decoction and acupuncture combined with Western medicine in acute severe stroke patients.World journal of clinical cases · 2023Article
- Severely Hypoperfused Brain Tissue Correlates with Final Infarct Volume Despite Recanalization in DMVO Stroke.Journal of the Belgian Society of Radiology · 2023Article
- Cardio-cerebral infarction in left MCA strokes: a case series and literature review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Review
- Early Neurological Improvement Predicts Clinical Outcome After Thrombectomy for Distal Medium Vessel Occlusions.Frontiers in neurology · 2022Article
- Value of high-density sign on CT images after mechanical thrombectomy for large vessel occlusion in predicting hemorrhage and unfavorable outcome.The neuroradiology journal · 2021Article
- Early Venous Filling Following Thrombectomy: Association With Hemorrhagic Transformation and Functional Outcome.Frontiers in neurology · 2021Article
- Hemorrhagic Transformation After Ischemic Stroke: Mechanisms and Management.Frontiers in neurology · 2021Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hemorrhagic transformation (HT) is one of the most common adverse events related to acute ischemic stroke (AIS) that affects the treatment plan and clinical outcome. Identification of a sensitive radiological marker may influence the controversial thrombolytic decision in the setting of AIS and may at a minimum indicate more intensive monitoring or further prophylactic interventions. In this article we summarize possible radiological biomarkers and the role of different radiological modalities including computed tomography (CT), magnetic resonance imaging, angiography, and ultrasound in predicting HT. Different radiological indices of early ischemic changes, large ischemic lesion volume, severe blood flow restriction, blood-brain barrier disruption, poor collaterals and high blood flow velocities have been reported to be associated with higher risk of HT. The current levels of evidence of the available studies highlight the role of the different CT perfusion parameters in predicting HT. Further large standardized studies are recommended to compare the sensitivity and specificity of the different radiological markers combined and delineate the most reliable predictor.
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