Evidence map›Paper›PMID 31970899›Full record

ArticleJournal of cellular and molecular medicine2020

Co-expression of glycosylated aquaporin-1 and transcription factor NFAT5 contributes to aortic stiffness in diabetic and atherosclerosis-prone mice.

Rosalinda Madonna, Vanessa Doria, Anikó Görbe, Nino Cocco, Péter Ferdinandy, Yong-Jian Geng, Sante Donato Pierdomenico, Raffaele De Caterina

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. LARP7 overexpression alleviates aortic senescence and atherosclerosis.Journal of cellular and molecular medicine · 2024
    Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Rosalinda MadonnaInstitute of Cardiology, University of Pisa, Pisa, Italy.ORCID 0000-0001-6455-2777
Vanessa DoriaCenter of Excellence on Aging and Regenerative Medicine (CeSI-Met), "G. d'Annunzio" University Chieti, Chieti, Italy.
Anikó GörbeDepartment of Pharmacology and Pharmacotherapy, Semmelweis University, Budapest, Hungary.
Nino CoccoTor Vergata University Hospital, Rome, Italy.
Péter FerdinandyDepartment of Pharmacology and Pharmacotherapy, Semmelweis University, Budapest, Hungary.
Yong-Jian GengCenter for Cardiovascular Biology and Atherosclerosis Research, McGovern School of Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA.
Sante Donato PierdomenicoInstitute of Cardiology, "G. d'Annunzio" University, Chieti, Italy.
Raffaele De CaterinaInstitute of Cardiology, University of Pisa, Pisa, Italy.
Semmelweis University · HUUniversity of Chieti-Pescara · ITUniversity of Pisa · ITThe University of Texas Health Science Center at Houston · USUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increased stiffness characterizes the early change in the arterial wall with subclinical atherosclerosis. Proteins inducing arterial stiffness in diabetes and hypercholesterolaemia are largely unknown. This study aimed at determining the pattern of protein expression in stiffening aorta of diabetic and hypercholesterolaemic mice. Male Ins

Indexed as

Vascular StiffnessAnimalsAquaporin 1AtherosclerosisCollagen Type IIICytoskeletonDiabetes Mellitus, ExperimentalElastinGlycosylationMaleMice, Inbred C57BLMuscle, SmoothNADPH OxidasesNitric Oxide SynthasePhenotypeProtein IsoformsAquaporin 1Collagen Type IIIElastinNADPH OxidasesNfat5 protein, mouseNitric Oxide SynthaseProtein IsoformsTranscription FactorsVascular Cell Adhesion Molecule-1arterial stiffeningcytoskeletal remodellingdiabeteshypercholesterolaemiahyperosmolaritysubclinical atherosclerosis

Identifiers

PMID31970899
PMCPMC7077545
OpenAlexW3000765679

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.