ReviewHemodialysis international. International Symposium on Home Hemodialysis2020
Three compartment bioimpedance spectroscopy in the nutritional assessment and the outcome of patients with advanced or end stage kidney disease: What have we learned so far?
Review in Hemodialysis international. International Symposium on Home Hemodialysis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Lean tissue mass is associated with adverse outcomes across different stages of chronic kidney disease: a systematic review and meta-analysis.Scientific reports · 2026Pooled it
- Prognostic Significance of Baseline Lean Tissue Mass Percentage in Incident Peritoneal Dialysis Patients.Kidney medicine · 2026Article
- Optimizing hemodialysis management using bioelectrical impedance analysis: emphasizing the significance of the phase angle.Renal failure · 2025Review
- Practical Guide to Nutritional Assessment in CKD: Current Tools, Emerging Technologies, and Future Directions.Clinical journal of the American Society of Nephrology : CJASN · 2025Review
- Exploring Biomarkers for Excess Extracellular Fluid in the Context of Physical Function in Chronic Kidney Disease Patients.Journal of personalized medicine · 2024Article
- Article
- Modified creatinine index as a marker of skeletal muscle mass in peritoneal dialysis patients.Clinical kidney journal · 2024Article
- Sarcopenia diagnosed by ultrasound-assessed quadriceps muscle thickness and handgrip strength predicts mortality in patients on hemodialysis.Journal of nephrology · 2024Article
- Review
- Application of Bioelectrical Impedance Analysis in Nutritional Management of Patients with Chronic Kidney Disease.Nutrients · 2023Review
- Chronic kidney disease-related sarcopenia as a prognostic indicator in elderly haemodialysis patients.BMC nephrology · 2023Observational
- Malnutrition Patterns in Children with Chronic Kidney Disease.Life (Basel, Switzerland) · 2023Review
- Predicting mortality risk in dialysis: Assessment of risk factors using traditional and advanced modeling techniques within the Monitoring Dialysis Outcomes initiative.Hemodialysis international. International Symposium on Home Hemodialysis · 2023Article
- The Impact of Volume Overload on the Longitudinal Change of Adipose and Lean Tissue Mass in Incident Chinese Peritoneal Dialysis Patients.Nutrients · 2022Observational
- Can Overnutrition Lead to Wasting?-The Paradox of Diabetes Mellitus in End-Stage Renal Disease Treated with Maintenance Hemodialysis.Nutrients · 2022Observational
- Body composition monitoring in children and adolescents: reproducibility and reference values.European journal of pediatrics · 2021Article
- Review
- Association between relative fat mass, uric acid, and insulin resistance in children with chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2021Article
- Estimation of Muscle Mass in the Integrated Assessment of Patients on Hemodialysis.Frontiers in nutrition · 2021Review
- Comparison of bioimpedance spectroscopy and dual energy X-ray absorptiometry for assessing body composition changes in obese children during weight loss.European journal of clinical nutrition · 2021Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bioimpedance spectroscopy (BIS) is an easily applicable tool to assess body composition. The three compartment model BIS (3C BIS) conventionally expresses body composition as lean tissue index (LTI) (lean tissue mass [LTM]/height in meters squared) and fat tissue index (FTI) (adipose tissue mass/height in meters squared), and a virtual compartment reflecting fluid overload (FO). It has been studied extensively in relation to diagnosis and treatment guidance of fluid status disorders in patients with advanced-stage or end-stage renal disease. It is the aim of this article to provide a narrative review on the relevance of 3C BIS in the nutritional assessment in this population. At a population level, LTI decreases after the start of hemodialysis, whereas FTI increases. LTI below the 10th percentile is a consistent predictor of outcome whereas a low FTI is predominantly associated with outcome when combined with a low LTI. Recent research also showed the connection between low LTI, inflammation, and FO, which are cumulatively associated with an increased mortality risk. However, studies toward nutritional interventions based on BIS data are still lacking in this population. In conclusion, 3C BIS, by disentangling the components of body mass index, has contributed to our understanding of the relevance of abnormalities in different body compartments in chronic kidney disease patients, and appears to be a valuable prognostic tool, at least at a population level. Studies assessing the effect of BIS guided nutritional intervention could further support its use in the daily clinical care for renal patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.