Evidence map›Paper›PMID 31970756›Full record

ArticleBiometrics2020

Nonnegative decomposition of functional count data.

Daniel Backenroth, Russell T Shinohara, Jennifer A Schrack, Jeff Goldsmith

Open access · greenAbstract read
In one paragraph

Article in Biometrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Daniel BackenrothDepartment of Biostatistics, Mailman School of Public Health, Columbia University, New York City, New York.ORCID 0000-0002-9581-8870
Russell T ShinoharaPenn Statistics in Imaging and Visualization Center, Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.ORCID 0000-0001-8627-8203
Jennifer A SchrackDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Jeff GoldsmithDepartment of Biostatistics, Mailman School of Public Health, Columbia University, New York City, New York.
City University of New York · USJohns Hopkins University · USPenn Center for AIDS Research · US

Funding

Statistical Methods for Multilevel Multivariate Functional StudiesR01NS060910 · NINDS · JOHNS HOPKINS UNIVERSITY · PI Ciprian M Crainiceanu · 2009 to 2026
$8.3M
Inter-modal Coupling Image AnalyticsR01MH112847 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI Theodore Satterthwaite, Russell Takeshi Shinohara · 2017 to 2026
$5.9M
Functional data analytics for kinematic assessments of motor controlR01NS097423 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GOLDSMITH, JEFF · 2016 to 2020
$1.8M
Statistical methods for large and complex databases of ultra-high-dimensionalR01NS085211 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI SHINOHARA, RUSSELL TAKESHI · 2013 to 2017
$1.8M
Statistical methods for biosignals with varying domainsR01HL123407 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI CRAINICEANU, CIPRIAN M · 2014 to 2017
$1.6M
Spatiotemporal Modeling of MRI Brain Lesion Trajectories of Biomarker DiscoveryR21NS093349 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI ELOYAN, ANI, SHINOHARA, RUSSELL TAKESHI · 2016 to 2017
$454k
Generalized, multilevel functional response models applied to accelerometer data.R21EB018917 · NIBIB · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GOLDSMITH, JEFF · 2015 to 2016
$395k
NHLBI NIH HHS R01 HL123407NIBIB NIH HHS R21 EB018917NIMH NIH HHS R01 MH112847NINDS NIH HHS R01 NS060910NINDS NIH HHS R01 NS085211NINDS NIH HHS R01 NS097423NINDS NIH HHS R21 NS093349
6 · The paper itself

Abstract

We present a novel decomposition of nonnegative functional count data that draws on concepts from nonnegative matrix factorization. Our decomposition, which we refer to as NARFD (nonnegative and regularized function decomposition), enables the study of patterns in variation across subjects in a highly interpretable manner. Prototypic modes of variation are estimated directly on the observed scale of the data, are local, and are transparently added together to reconstruct observed functions. This contrasts with generalized functional principal component analysis, an alternative approach that estimates functional principal components on a transformed scale, produces components that typically vary across the entire functional domain, and reconstructs observations using complex patterns of cancellation and multiplication of functional principal components. NARFD is implemented using an alternating minimization algorithm, and we evaluate our approach in simulations. We apply NARFD to an accelerometer dataset comprising observations of physical activity for healthy older Americans.

Indexed as

AlgorithmsAgedHumansaccelerometersfunctional datanonnegative matrix factorization

Identifiers

PMID31970756
PMCPMC7375931
OpenAlexW3001789854

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.